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The endocannabinoid system: a general view and latest additions

The endocannabinoid system: a general view and latest additions

http://www.wikidata.org/entity/Q35639524

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The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporter Cannabinoids and intestinal motility: welcome to CB2 receptors Lipidomic Analysis of Endocannabinoid Signaling: Targeted Metabolite Identification and Quantification To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making The molecular connections between the cannabinoid system and endometriosis Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats.Potential role of the endocannabinoid receptor antagonist rimonabant in the management of cardiometabolic risk: a narrative review of available data Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction Loss of cannabinoid receptor CB1 induces preterm birth.The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.Identification of palmitoyl protein thioesterase 1 in human THP1 monocytes and macrophages and characterization of unique biochemical activities for this enzyme Cannabinoid Regulation of Brain Reward Processing with an Emphasis on the Role of CB1 Receptors: A Step Back into the Future Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease Are TRP channels involved in sperm development and function?Physiological and molecular determinants of embryo implantation Opposite effects of methanandamide on lipopolysaccharide-induced prostaglandin E2 and F2α synthesis in uterine explants from pregnant mice.How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches.Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase.Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment.Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome.The endocannabinoid system and pain Prostamides (prostaglandin-ethanolamides) and their pharmacology.Plasma concentrations of endocannabinoids and related primary fatty acid amides in patients with post-traumatic stress disorder.The abused inhalant toluene differentially modulates excitatory and inhibitory synaptic transmission in deep-layer neurons of the medial prefrontal cortex.Manipulation of Arabidopsis fatty acid amide hydrolase expression modifies plant growth and sensitivity to N-acylethanolamines.Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol N-acylethanolamine (NAE) inhibits growth in Arabidopsis thaliana seedlings via ABI3-dependent and -independent pathways.Endocannabinoids are conserved inhibitors of the Hedgehog pathway.Endocannabinoids and cardiovascular prevention: real progress?The endocannabinoid system: physiology and pharmacology.

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P2860

The endocannabinoid system: a general view and latest additions

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Luciano De Petrocellis

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Maria Grazia Cascio

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P2860

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo

Brain monoglyceride lipase participating in endocannabinoid inactivation

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors.

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

Evidence against the presence of an anandamide transporter

Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling

Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues

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Vincenzo Di Marzo

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endocannabinoid system

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