Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

about

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim.

P2860

Q35731554-6F3ED662-3CC2-4BD6-B8B0-2097995674C5

P2860

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

Item

http://www.wikidata.org/entity/Q35639894

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@ast

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@en

type

Item

label

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@ast

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@en

prefLabel

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@ast

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@en

P1476

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

@en

P2093

Andrew D Carlson

http://www.w3.org/2001/XMLSchema#string

Gordon C Shore

http://www.w3.org/2001/XMLSchema#string

Jack D Bracken

http://www.w3.org/2001/XMLSchema#string

Mai Nguyen

http://www.w3.org/2001/XMLSchema#string

Patrick G Harran

http://www.w3.org/2001/XMLSchema#string

P2860

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based Design

Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH3 Domain

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Discovering high-affinity ligands for proteins: SAR by NMR

ABT-199, a new Bcl-2-specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia.

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.

9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers.

P304

3612-3616

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.TETLET.2015.01.191

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

James H Frederich

P577

2015-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26019371

http://www.w3.org/2001/XMLSchema#string

P932

4442084

http://www.w3.org/2001/XMLSchema#string

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

about

P2860

P2860

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932