Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity
about
Disentangling the many layers of eukaryotic transcriptional regulationDrosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19Role of HOXA9 in leukemia: dysregulation, cofactors and essential targetsHox proteins display a common and ancestral ability to diversify their interaction mode with the PBC class cofactors.Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neuronsDistinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnershipA combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity.Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired.The homeodomain transcription factors antennapedia and POU-M2 regulate the transcription of the steroidogenic enzyme gene Phantom in the silkworm.To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.Mechanisms of Specificity for Hox Factor Activity.New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA.Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.Hox functional diversity: Novel insights from flexible motif folding and plastic protein interaction.Low affinity binding site clusters confer hox specificity and regulatory robustness.Hox transcriptional specificity despite a single class of cofactors: are flexible interaction modes the key? Plasticity in Hox/PBC interaction modes as a common molecular strategy for shaping Hox transcriptional activities.Nuclear microenvironments modulate transcription from low-affinity enhancers.Combinatorial action of Grainyhead, Extradenticle and Notch in regulating Hox mediated apoptosis in Drosophila larval CNS.Non-specificity of transcription factor function in Drosophila melanogaster.Hox5 Paralogous Genes Modulate Th2 Cell Function during Chronic Allergic Inflammation via Regulation of Gata3.Revisiting the context dependence of cofactor-recruiting motifs.Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites
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P2860
Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Variable motif utilization in ...... formation controls specificity
@ast
Variable motif utilization in ...... formation controls specificity
@en
type
label
Variable motif utilization in ...... formation controls specificity
@ast
Variable motif utilization in ...... formation controls specificity
@en
prefLabel
Variable motif utilization in ...... formation controls specificity
@ast
Variable motif utilization in ...... formation controls specificity
@en
P2093
P2860
P356
P1476
Variable motif utilization in ...... formation controls specificity
@en
P2093
Barbara Noro
Katherine M Lelli
Richard S Mann
P2860
P304
21122-21127
P356
10.1073/PNAS.1114118109
P407
P577
2011-12-12T00:00:00Z