The KGD motif of Epstein-Barr virus gH/gL is bifunctional, orchestrating infection of B cells and epithelial cells.
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Structural and Mechanistic Insights into the Tropism of Epstein-Barr VirusStuck in the middle: structural insights into the role of the gH/gL heterodimer in herpesvirus entryAssembly and architecture of the EBV B cell entry triggering complexChlamydia trachomatis polymorphic membrane protein D is a virulence factor involved in early host-cell interactions.The Epstein-Barr virus (EBV) glycoprotein B cytoplasmic C-terminal tail domain regulates the energy requirement for EBV-induced membrane fusion.Herpes virus fusion and entry: a story with many characters.Epstein-Barr virus glycoprotein gB and gHgL can mediate fusion and entry in trans, and heat can act as a partial surrogate for gHgL and trigger a conformational change in gB.The conserved disulfide bond within domain II of Epstein-Barr virus gH has divergent roles in membrane fusion with epithelial cells and B cellsMembrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacersScanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL.Nonmuscle myosin heavy chain IIA mediates Epstein-Barr virus infection of nasopharyngeal epithelial cells.A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion.The large groove found in the gH/gL structure is an important functional domain for Epstein-Barr virus fusion.Identification of the human herpesvirus 6A gQ1 domain essential for its functional conformation.The BDLF3 gene product of Epstein-Barr virus, gp150, mediates non-productive binding to heparan sulfate on epithelial cells and only the binding domain of CD21 is required for infection.The Cytoplasmic Tail Domain of Epstein-Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment.Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins.Implication of human herpesviruses in oncogenesis through immune evasion and supression.Epstein-Barr virus infection mechanismsComparative Mutagenesis of Pseudorabies Virus and Epstein-Barr Virus gH Identifies a Structural Determinant within Domain III of gH Required for Surface Expression and Entry FunctionEBV glycoproteins: where are we now?Pathogenesis of Gastric Cancer: Genetics and Molecular Classification.A comparative review of viral entry and attachment during large and giant dsDNA virus infections.Epstein-Barr virus fusion with epithelial cells triggered by gB is restricted by a gL glycosylation site.Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies.Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus.An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.Perspectives of Phage-Eukaryotic Cell Interactions to Control Epstein-Barr Virus Infections.The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis.
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P2860
The KGD motif of Epstein-Barr virus gH/gL is bifunctional, orchestrating infection of B cells and epithelial cells.
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2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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name
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@ast
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
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type
label
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@ast
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@en
prefLabel
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@ast
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@en
P2093
P2860
P356
P1433
P1476
The KGD motif of Epstein-Barr ...... B cells and epithelial cells.
@en
P2093
Cynthia L Rowe
Richard Longnecker
Theodore S Jardetzky
P2860
P356
10.1128/MBIO.00290-11
P577
2012-01-03T00:00:00Z