Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches - Wikidata - awgldk - TriplyDB

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

http://www.wikidata.org/entity/Q35652417

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A Role for Notch Signalling in Breast Cancer and Endocrine Resistance Targeting Notch to overcome radiation resistance Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer Identifying and targeting tumor-initiating cells in the treatment of breast cancer Notch: a key regulator of tumor angiogenesis and metastasis Notch signaling in prostate cancer: a moving target Targeting γ-secretase in breast cancer Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment Γ-secretase components as predictors of breast cancer outcome Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland The difficulty of targeting cancer stem cell niches Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo.Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis Mammary development and breast cancer: the role of stem cells NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice.MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis.Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.NILCO biomarkers in breast cancer from Chinese patients Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer.Estrogen signaling crosstalk: Implications for endocrine resistance in ovarian cancer.ERalpha-negative and triple negative breast cancer: molecular features and potential therapeutic approaches Targeting Notch signaling pathway to overcome drug resistance for cancer therapy Proliferation and enrichment of CD133(+) glioblastoma cancer stem cells on 3D chitosan-alginate scaffolds.Notch inhibitors for cancer treatment.Notch signaling in pediatric soft tissue sarcomas High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer.The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinoma.Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: novel therapeutic strategy for aggressive breast cancers.The pathological significance of Notch1 in oral squamous cell carcinoma.Role of Notch and its oncogenic signaling crosstalk in breast cancer.New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers Expression of Notch receptors, ligands, and target genes during development of the mouse mammary gland Active targeting of mesoporous silica drug carriers enhances γ-secretase inhibitor efficacy in an in vivo model for breast cancer.17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling.Notch signaling proteins: legitimate targets for cancer therapy.Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization.

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P2860

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

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Cross-talk between notch and t ...... s novel therapeutic approaches

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Cross-talk between notch and t ...... s novel therapeutic approaches

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Cross-talk between notch and t ...... s novel therapeutic approaches

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Cross-talk between notch and t ...... s novel therapeutic approaches

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Cancer Research

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Cross-talk between notch and t ...... s novel therapeutic approaches

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Adriano Marchese

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Amina Bashir

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Brian J Nickoloff

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Chindo Hicks

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Clodia Osipo

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Debra A Tonetti

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Debra Wyatt

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Deepali Bhandari

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Giovanni Antico

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Gwendolyn D'Souza

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P2860

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

Involvement of Notch1 in the development of mouse mammary tumors

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

E1A activates transcription of p73 and Noxa to induce apoptosis

High-level JAG1 mRNA and protein predict poor outcome in breast cancer

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

New colorimetric cytotoxicity assay for anticancer-drug screening

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5226-5235

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