B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice. - Wikidata - awgldk - TriplyDB

B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice.

B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice.

http://www.wikidata.org/entity/Q35658606

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Interleukin-5 supports the expansion of fas ligand-expressing killer B cells that induce antigen-specific apoptosis of CD4(+) T cells and secrete interleukin-10 IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice Regulatory B10 cell development and function B10 cell regulation of health and disease.Critical role for thymic CD19+CD5+CD1dhiIL-10+ regulatory B cells in immune homeostasis.Control of lupus nephritis by changes of gut microbiota.T follicular helper cells mediate expansion of regulatory B cells via IL-21 in Lupus-prone MRL/lpr mice.Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance.Mincle and human B cell function IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus.IL-10-producing regulatory B cells (B10 cells) in autoimmune disease.Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells.Accelerated atherosclerosis in SLE: mechanisms and prevention approaches.Autoimmunity in 2012.Contributions of B cells to lupus pathogenesis B-type suppression: a role played by "regulatory B cells" or "regulatory plasma cells"?Targeting IL-10 in auto-immune diseases.Signals controlling the development and activity of regulatory B-lineage cells.IL-10-independent regulatory B-cell subsets and mechanisms of action.Antibody-independent functions of B cells: a focus on cytokines.B Cells with Regulatory Function in Animal Models of Autoimmune and Non-Autoimmune Diseases Regulatory B cells mediate tolerance to apoptotic self in health: implications for disease.Cytokine-producing B cells: a translational view on their roles in human and mouse autoimmune diseases.Potential importance of B cells in aging and aging-associated neurodegenerative diseases.IL-35, as a newly proposed homeostasis-associated molecular pattern, plays three major functions including anti-inflammatory initiator, effector, and blocker in cardiovascular diseases.Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice.Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr) mice.Clinical significance of regulatory B cells in the peripheral blood of patients with oesophageal cancer.B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis.Gr-1(high) CD11b+ cells suppress B cell differentiation and lupus-like disease in lupus-prone male mice.Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice.LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

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P2860

B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice.

http://www.wikidata.org/entity/Q35658606

description

2011 nî lūn-bûn

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2011年の論文

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name

B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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JIMMUNOL.1102456

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Journal of Immunology

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B cell-derived IL-10 does not ...... immunity in MRL.Fas(lpr) mice.

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Axel Roers

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Lino L Teichmann

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Mark J Shlomchik

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Michael Kashgarian

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P2860

Interleukin-10 and the interleukin-10 receptor

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus.

CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients.

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.

B cells regulate autoimmunity by provision of IL-10.

Prevention of arthritis by interleukin 10-producing B cells.

Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

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678-685

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2

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188

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Casey T. Weaver

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51866648

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22156495

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3253138

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