JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.
about
Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeuticsCross-linking protein glutathionylation mediated by O2-arylated bis-diazeniumdiolate "Double JS-K".Cellular distribution studies of the nitric oxide-generating antineoplastic prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate formulated in Pluronic P123 micelles.JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cellsA reactive oxygen species activation mechanism contributes to JS-K-induced apoptosis in human bladder cancer cells.N-(2-Hydroxypropyl)methacrylamide Copolymer-Drug Conjugates for Combination Chemotherapy of Acute Myeloid LeukemiaEffects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI.Thiol Modification By Pharmacologically Active Agents of the Diazeniumdiolate ClassNitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme.ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastomaNitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells.Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation.NOS Expression and NO Function in Glioma and Implications for Patient Therapies.Role of Glutathione-S-transferases in neurological problems.The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation.Glutathione S -transferase π: a potential role in antitumor therapy
P2860
Q26782525-11A775B5-8019-4E48-8815-DE739A11C75BQ30422929-80A3E134-657D-43DE-907C-881ABC0BE082Q33565776-D445CD7C-134B-4232-B242-18ECCD5BFD47Q33733592-C4B40382-FBBE-4C8E-BCE1-9E36815BFEDFQ36149908-5DCFE26D-DB9C-429E-8CAB-9E0DCB816A24Q36722841-CC4401AF-1217-44DA-BA5E-D0075E94678CQ36741601-A92BB604-C83D-4283-A4A4-FE6B9ECAC99FQ36754617-0EC2EEBB-3C05-4CB5-8980-A04B307D521DQ37133470-7D35BE23-9A75-49E1-B3A7-B6E4EBD0FCCFQ37330827-F7A8D8D6-3263-46A3-B422-AE7BD57A3E8FQ37668192-E5DAC646-3DF3-42EF-AE96-73553DA78331Q37697400-BA280D65-38E4-405F-9560-A615FAF07352Q37701349-C8FC1EAB-BDBF-4F8D-B7BF-FBB0AF2AD1A8Q38842322-9ECF3A4E-B690-4C40-9FDD-8C0878293446Q38992254-EECA5E53-E517-4BFC-9ADF-FD333DD5DC85Q48222651-3CF9E2E3-9438-4F35-AC4F-FF5CA5B070F1Q58694500-A36C0B6B-F737-4D01-AE05-4F30ED0B140F
P2860
JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@ast
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@en
type
label
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@ast
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@en
prefLabel
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@ast
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@en
P2093
P2860
P1433
P1476
JS-K, a glutathione S-transfer ...... activity in malignant gliomas.
@en
P2093
Anna Papazoglou
Anna Werres
Astrid Weyerbrock
Brunhilde Baumer
Evangelos Kogias
Joseph E Saavedra
Larry K Keefer
Nadja Osterberg
Nikolaos Psarras
Stefanie Bette
P2860
P304
497-510; discussion 510
P356
10.1227/NEU.0B013E31823209CF
P407
P577
2012-02-01T00:00:00Z