Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

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http://www.wikidata.org/entity/Q35664304
Axonal transport of AAV9 in nonhuman primate brain.AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice.Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B.Evaluation of intrathecal routes of administration for adeno-associated virus vectors in large animals.Efficient CNS targeting in adult mice by intrathecal infusion of single-stranded AAV9-GFP for gene therapy of neurological disorders.Systemic and Persistent Muscle Gene Expression in Rhesus Monkeys with a Liver De-Targeted Adeno-Associated Virus Vector.Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors.Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies.Severe toxicity in nonhuman primates and piglets following high-dose intravenous administration of an AAV vector expressing human SMN.Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space.Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation.Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS.
P2860

Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

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http://www.wikidata.org/entity/Q35664304
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
@zh-tw
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name
Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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Widespread gene transfer in th ...... AAV9 into the cisterna magna.
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P478
P577
P5875
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P932