Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques. - Wikidata - awgldk - TriplyDB

Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques.

Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques.

http://www.wikidata.org/entity/Q35666402

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Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?Antiretroviral pharmacology in mucosal tissues Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug delivery Vaginal drug distribution modeling MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel Formulation, pharmacokinetics and pharmacodynamics of topical microbicides.A review of nanotechnological approaches for the prophylaxis of HIV/AIDS.Historical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes.Pharmacokinetics and preliminary safety study of pod-intravaginal rings delivering antiretroviral combinations for HIV prophylaxis in a macaque model.Nanoparticle-based drug delivery to the vagina: a review.A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate.Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.Rectal microbicide development.A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study).The sheep as a model of preclinical safety and pharmacokinetic evaluations of candidate microbicides Microbicides for HIV prevention.HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model.Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques.Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.In search of the optimal delivery method for anti-HIV microbicides: are intravaginal rings the way forward?Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.Overcoming pharmacologic sanctuaries.Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model.Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates.Future prospects and perspectives on microbicides.Antiretroviral bioanalysis methods of tissues and body biofluids.Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention.The Promise of Antiretrovirals for HIV Prevention.Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application.Pharmacokinetic and safety analyses of tenofovir and tenofovir-emtricitabine vaginal tablets in pigtailed macaques.The development of rectal microbicides for HIV prevention.An overview of antiretroviral pre-exposure prophylaxis of HIV infection.Non-human primate models of hormonal contraception and HIV.Comparison of the Pharmacokinetics and Pharmacodynamics of Single-Dose Tenofovir Vaginal Film and Gel Formulation (FAME 05).Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice.Exploring unsaturated fatty acid cholesteryl esters as transdermal permeation enhancers.Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing.Efficacy of Vaginally Administered Gel Containing Emtricitabine and Tenofovir Against Repeated Rectal SHIV Exposures in Macaques.

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P2860

Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques.

http://www.wikidata.org/entity/Q35666402

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Pharmacokinetics of tenofovir ...... ofovir gel to rhesus macaques.

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Pharmacokinetics of tenofovir ...... ofovir gel to rhesus macaques.

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Pharmacokinetics of tenofovir ...... ofovir gel to rhesus macaques.

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Pharmacokinetics of tenofovir ...... ofovir gel to rhesus macaques.

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Antimicrobial Agents and Chemotherapy

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Pharmacokinetics of tenofovir ...... ofovir gel to rhesus macaques.

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Angela Kashuba

http://www.w3.org/2001/XMLSchema#string

Jeffrey Roberts

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Joseph Romano

http://www.w3.org/2001/XMLSchema#string

Nicole White

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Philip Allen

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Ruili Wang

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P2860

Preexposure chemoprophylaxis for HIV prevention in men who have sex with men

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

Anal sex among HIV-seronegative women at high risk of HIV exposure. The HIVNET Vaccine Preparedness Study 2 Protocol Team.

Phosphorylation of nucleoside analog antiretrovirals: a review for clinicians.

Transvaginal progesterone: evidence for a new functional 'portal system' flowing from the vagina to the uterus.

Advances in the Development of Microbicides for the Prevention of HIV Infection.

Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients

Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis

Condom effectiveness in reducing heterosexual HIV transmission.

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103-109

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10.1128/AAC.00597-11

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1

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56

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2011-10-10T00:00:00Z

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21986823

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3256015

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