Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
about
Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMPBST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activityFGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complexMT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell developmentRegulation of membrane type-1 matrix metalloproteinase activation by proprotein convertasesCollagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expressionConnective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal developmentAnnexin II regulates fibrin homeostasis and neoangiogenesis in vivoElucidation of the potential roles of matrix metalloproteinases in skeletal biologyMatrix metalloproteinases: old dogs with new tricksMolecular underpinnings of corneal angiogenesis: advances over the past decadeAssociation of Common Variants in MMPs with Periodontitis RiskCorneal neovascularization and the utility of topical VEGF inhibition: ranibizumab (Lucentis) vs bevacizumab (Avastin)Moving targets: Emerging roles for MMPs in cancer progression and metastasisAnthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activityMT1-MMP recognition by ERM proteins and its implication in CD44 sheddingMatrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisUtilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding theHomophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWVThe fibroblast growth factor receptor, FGFR3, forms gradients of intact and degraded protein across the growth plate of developing bovine ribsCalmodulin inhibitors trigger the proteolytic processing of membrane type-1 matrix metalloproteinase, but not its shedding in glioblastoma cellsCritical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossificationMembrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesisSoluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survivalType I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal developmentRegulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in EndometriosisDifferential involvement of MMP-2 and VEGF during muscle stretch- versus shear stress-induced angiogenesisCross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivoCdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activationMembrane type 1-matrix metalloproteinase (MMP)-associated MMP-2 activation increases in the rat ovary in response to an ovulatory dose of human chorionic gonadotropinRegulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterusTie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defectsMechanistic Insights into the Anti-angiogenic Activity of Trypanosoma cruzi Protein 21 and its Potential Impact on the Onset of Chagasic CardiomyopathyMatrix metalloproteinases and the regulation of tissue remodellingHow matrix metalloproteinases regulate cell behaviorFunctional interplay between endothelial nitric oxide synthase and membrane type 1 matrix metalloproteinase in migrating endothelial cells.Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices.Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events.A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis.
P2860
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P2860
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@ast
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@en
type
label
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@ast
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@en
prefLabel
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@ast
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@en
P2093
P2860
P356
P1476
Impaired endochondral ossifica ...... ype matrix metalloproteinase I
@en
P2093
Baaklini GY
Soininen R
Tryggvason K
P2860
P304
P356
10.1073/PNAS.060037197
P407
P577
2000-04-01T00:00:00Z