Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
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Update on Pyrin Functions and Mechanisms of Familial Mediterranean FeverThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseThe cytoskeleton in cell-autonomous immunity: structural determinants of host defenceAutoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.Multiple Serum Cytokine Profiling to Identify Combinational Diagnostic Biomarkers in Attacks of Familial Mediterranean FeverAutoinflammatory Skin Disorders: The Inflammasomme in Focus.F-actin dampens NLRP3 inflammasome activity via Flightless-I and LRRFIP2.Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activationGeoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review.Biologic therapy in familial Mediterranean fever.Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms.Mechanisms governing inflammasome activation, assembly and pyroptosis induction.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation.Can the Thiol/Disulfide Imbalance Be a Predictor of Colchicine Resistance in Familial Mediterranean Fever?Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.Septins restrict inflammation and protect zebrafish larvae from Shigella infection.Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiencyInflammation on the move.Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission.Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells.Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseases.MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway.Inflammasome activation and assembly at a glance.Functions of actin-interacting protein 1 (AIP1)/WD repeat protein 1 (WDR1) in actin filament dynamics and cytoskeletal regulation.Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome.Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.Function and mechanism of the pyrin inflammasome.Emerging Concepts in Innate Immunity.Use of zebrafish to study Shigella infection.A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 InflammasomeAmyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system
P2860
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P2860
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@ast
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@en
type
label
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@ast
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@en
prefLabel
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@ast
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@en
P2093
P2860
P50
P356
P1476
Aberrant actin depolymerizatio ...... dependent on IL-18, not IL-1β.
@en
P2093
Daniel L Kastner
Hyun-Ja Ko
Jae Jin Chae
Ladina DiRago
Louise Cengia
Man Lyang Kim
Roslynn A Stirzaker
Yong Hwan Park
P2860
P304
P356
10.1084/JEM.20142384
P407
P50
P577
2015-05-25T00:00:00Z