The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
about
Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathyCooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathyTitin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle RemodelingCardiac thin filament regulation and the Frank-Starling mechanismThe cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fractionDynamic Alterations to α-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte MitosisPathophysiological defects and transcriptional profiling in the RBM20-/- rat modelA regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain.From Tusko to Titin: the role for comparative physiology in an era of molecular discoveryThe vertebrate muscle Z-disc: sarcomere anchor for structure and signallingTargeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophyAnisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretchNovex-3, the tiny titin of muscle.Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy.Influence of V54M mutation in giant muscle protein titin: a computational screening and molecular dynamics approach.Mechanical analysis of Drosophila indirect flight and jump musclesSingle molecule force spectroscopy on titin implicates immunoglobulin domain stability as a cardiac disease mechanism.Short read (next-generation) sequencing: a tutorial with cardiomyopathy diagnostics as an exemplar.Micromechanical regulation in cardiac myocytes and fibroblasts: implications for tissue remodelingThe diastolic function to cyclic variation of myocardial ultrasonic backscatter relation: the influence of parameterized diastolic filling (PDF) formalism determined chamber propertiesSecondary and tertiary structure elasticity of titin Z1Z2 and a titin chain model.Integrating multi-scale data to create a virtual physiological mouse heart.Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice.Hierarchical extensibility in the PEVK domain of skeletal-muscle titin.Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy.Digital transcriptome analysis indicates adaptive mechanisms in the heart of a hibernating mammal.Mechanobiology of cardiomyocyte developmentDiscovery through the computational microscope.Left ventricular torsional mechanics and myocardial iron load in beta-thalassaemia major: a potential role of titin degradation.Transmural heterogeneity of cellular level power output is reduced in human heart failure.Titin diversity--alternative splicing gone wildTertiary and secondary structure elasticity of a six-Ig titin chain.The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.Myofilament length dependent activationExcision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffnessModular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications.Physiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscleHsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes.Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.
P2860
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P2860
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@ast
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@en
type
label
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@ast
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@en
prefLabel
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@ast
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@en
P1433
P1476
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
@en
P2093
Henk L Granzier
Siegfried Labeit
P304
P356
10.1161/01.RES.0000117769.88862.F8
P577
2004-02-01T00:00:00Z