Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling
about
CAR T Cell Therapy: A Game Changer in Cancer TreatmentExploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinicHarnessing the Microbiome to Enhance Cancer ImmunotherapyToll-like receptor agonist therapy can profoundly augment the antitumor activity of adoptively transferred CD8(+) T cells without host preconditioning.Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion.The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs.Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells and IL-12.
P2860
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P2860
Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
@zh-hk
2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
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Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
@en
type
label
Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
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Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
@en
prefLabel
Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
@ast
Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
@en
P2093
P2860
P1476
Dendritic Cells in Irradiated ...... Tc17 Cells via IL12 Signaling
@en
P2093
Chrystal M Paulos
David J Cole
Kristina M Schwartz
Logan W Huff
Mark P Rubinstein
Michelle H Nelson
Sreenath Kundimi
P2860
P304
P356
10.1158/1078-0432.CCR-14-2294
P407
P577
2015-04-22T00:00:00Z