Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.
about
New drugs in prostate cancerArginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.Drug-induced amino acid deprivation as strategy for cancer therapy.Phase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers.Arginine dependence of tumor cells: targeting a chink in cancer's armor.Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.The Metabolic Phenotype of Prostate Cancer.Development and evaluation of a host-targeted antiviral that abrogates herpes simplex virus replication through modulation of arginine-associated metabolic pathways.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.A phase 1/1B trial of ADI-PEG 20 plus nab-paclitaxel and gemcitabine in patients with advanced pancreatic adenocarcinoma.The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells.How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress-Therapeutic Implications.Linking cellular metabolism and metabolomics to risk-stratification of prostate cancer clinical aggressiveness and potential therapeutic pathways
P2860
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P2860
Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@ast
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@en
type
label
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@ast
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@en
prefLabel
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@ast
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@en
P2093
P2860
P1476
Phase I Trial of Arginine Depr ...... vanced Malignant Solid Tumors.
@en
P2093
Benjamin K Tomlinson
Chong-Xian Pan
I-Yeh Gong
James A Thomson
John S Bomalaski
Monica Diaz
Mrinal P Dutia
Nichole Mahaffey
Primo N Lara
Taiwo Akande
P2860
P304
P356
10.1158/1078-0432.CCR-14-2610
P407
P577
2015-03-04T00:00:00Z