Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer - Wikidata - awgldk - TriplyDB

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

http://www.wikidata.org/entity/Q35676763

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Animal cell differentiation patterns suppress somatic evolution Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB Cancer systems biology: a network modeling perspective Cancer evolution: mathematical models and computational inference Colon cryptogenesis: asymmetric budding Mechanical model of geometric cell and topological algorithm for cell dynamics from single-cell to formation of monolayered tissues with pattern Radiation-induced carcinogenesis: mechanistically based differences between gamma-rays and neutrons, and interactions with DMBA A simple mathematical model based on the cancer stem cell hypothesis suggests kinetic commonalities in solid tumor growth Stochastic Tunneling of Two Mutations in a Population of Cancer Cells Evolution of pre-existing versus acquired resistance to platinum drugs and PARP inhibitors in BRCA-associated cancers Vignettes from the field of mathematical biology: the application of mathematics to biology and medicine A calibrated agent-based computer model of stochastic cell dynamics in normal human colon crypts useful for in silico experiments.Stochastic dynamics and the evolution of mutations in stem cells A quantitative and dynamic model for plant stem cell regulation.Unraveling intestinal stem cell behavior with models of crypt dynamics A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency.STORM: a general model to determine the number and adaptive changes of epithelial stem cells in teleost, murine and human intestinal tracts.Multi-scale Modelling for Threshold Dependent Differentiation.The probable cell of origin of NF1- and PDGF-driven glioblastomas.Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.Nonlinear modelling of cancer: bridging the gap between cells and tumours A mathematical-biological joint effort to investigate the tumor-initiating ability of Cancer Stem Cells.In silico models of cancer Computational model of cell positioning: directed and collective migration in the intestinal crypt epithelium.Spatial dynamics of multistage cell lineages in tissue stratification.A reaction-diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells Patterns of proliferative activity in the colonic crypt determine crypt stability and rates of somatic evolution.Principles of regulation of self-renewing cell lineages.Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts.Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer?Effect of dedifferentiation on time to mutation acquisition in stem cell-driven cancers.Comparing a discrete and continuum model of the intestinal crypt Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers.Organ aging and susceptibility to cancer may be related to the geometry of the stem cell niche.A versatile mathematical work-flow to explore how Cancer Stem Cell fate influences tumor progression.The Interplay between Wnt Mediated Expansion and Negative Regulation of Growth Promotes Robust Intestinal Crypt Structure and Homeostasis.Using mathematical models to understand metabolism, genes, and disease The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis.Near Equilibrium Calculus of Stem Cells in Application to the Airway Epithelium Lineage

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Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

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Mathematical modeling of cell ...... crypt and in colorectal cancer

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Proceedings of the National Academy of Sciences of the United States of America

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Mathematical modeling of cell ...... crypt and in colorectal cancer

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Carina M Edwards

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Matthew D Johnston

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Philip K Maini

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S Jonathan Chapman

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P2860

The Hallmarks of Cancer

The role of chromosomal instability in tumor initiation.

A genetic model for colorectal tumorigenesis

Caught up in a Wnt storm: Wnt signaling in cancer

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt

Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models.

Methylation patterns and mathematical models reveal dynamics of stem cell turnover in the human colon

Mathematical models of the balance between apoptosis and proliferation.

Stem cell in gastrointestinal structure and neoplastic development.

Molecular and clinical basis for the regeneration of human gastrointestinal epithelia.

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colorectal cancer

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