Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate.
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Musashi2 is required for the self-renewal and pluripotency of embryonic stem cellsRapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machineryThe H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1rThe transcriptional regulation of pluripotencyThe roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generationConcise review: The Sox2-Oct4 connection: critical players in a much larger interdependent network integrated at multiple levelsThe extended pluripotency protein interactome and its links to reprogrammingBarrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeriaStemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cellsCombinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development.Sox2 uses multiple domains to associate with proteins present in Sox2-protein complexes.Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinomaElevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells.Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos.The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cellsSox2 expression is regulated by a negative feedback loop in embryonic stem cells that involves AKT signaling and FoxO1.Proteomics and pluripotencypiggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiationThe quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and ReprogrammingSOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence.Determination of protein interactome of transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors.Members of the NODE (Nanog and Oct4-associated deacetylase) complex and SOX-2 promote the initiation of a natural cellular reprogramming event in vivo.Analyses of Sox-B and Sox-E Family Genes in the Cephalopod Sepia officinalis: Revealing the Conserved and the Unusual.Zinc finger transcription factor CASZ1 interacts with histones, DNA repair proteins and recruits NuRD complex to regulate gene transcriptionGene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell DifferentiationSOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors.Mitotic phosphorylation of SOX2 mediated by Aurora kinase A is critical for the stem-cell like cell maintenance in PA-1 cells.SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cellsThe multiple roles for Sox2 in stem cell maintenance and tumorigenesis.Deconstructing stem cell population heterogeneity: single-cell analysis and modeling approaches.Systems biology provides new insights into the molecular mechanisms that control the fate of embryonic stem cells.Proteomics in studying cancer stem cell biology.Embryonic stem cell interactomics: the beginning of a long road to biological function.Role of mass spectrometry-based proteomics in the study of cellular reprogramming and induced pluripotent stem cells.Concise review: the involvement of SOX2 in direct reprogramming of induced neural stem/precursor cellsSox21 regulates the progression of neuronal differentiation in a dose-dependent manner.Landscape of the SOX2 protein-protein interactome.The dark side of SOX2: cancer - a comprehensive overview.Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation.
P2860
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P2860
Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@ast
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@en
type
label
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@ast
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@en
prefLabel
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@ast
Proteomic analysis of Sox2-ass ...... l regulator of stem cell fate.
@en
P2093
P2860
P356
P1433
P1476
Proteomic analysis of Sox2-ass ...... el regulator of stem cell fate
@en
P2093
Angie Rizzino
Briana D Ormsbee
Jesse L Cox
Joshua M Gilmore
Michelina Iacovino
Sunil K Mallanna
P2860
P304
P356
10.1002/STEM.494
P577
2010-10-01T00:00:00Z