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Biological effects of Mammalian translationally controlled tumor protein (TCTP) on cell death, proliferation, and tumorigenesisHuman Bop is a novel BH3-only member of the Bcl-2 protein familyHuman nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domainInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisFunctional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic proteinThe hepatitis C virus core protein contains a BH3 domain that regulates apoptosis through specific interaction with human Mcl-1Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependencyVaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family proteinIdentification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylationInhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteinsApoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesisA surface groove essential for viral Bcl-2 function during chronic infection in vivo.Insight to drug delivery aspects for colorectal cancerBH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisionsDynamics of Bcl-xL in water and membrane: molecular simulationsStructure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine γ-Herpesvirus 68TCTP protects from apoptotic cell death by antagonizing bax functionCompleting the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with BimBAX activation is initiated at a novel interaction siteHigh-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xLStructural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2)Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based DesignStructural Insights of tBid, the Caspase-8-activated Bid, and Its BH3 DomainBh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysisStructural basis of Deerpox virus-mediated inhibition of apoptosisDiscovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based MethodsHypericin in the Dark: Foe or Ally in Photodynamic Therapy?Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosisActive fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergenceDirect Activation of Bax Protein for Cancer TherapyMapping the intrinsically disordered properties of the flexible loop domain of Bcl-2: a molecular dynamics simulation study.A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus ORF virusUnravelling the bcl-2 apoptosis code with a simple model system.Reconstitution and engineering of apoptotic protein interactions on the bacterial cell surface.Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin.Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy.Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Structural biology of the Bcl-2 family of proteins.
@ast
Structural biology of the Bcl-2 family of proteins.
@en
type
label
Structural biology of the Bcl-2 family of proteins.
@ast
Structural biology of the Bcl-2 family of proteins.
@en
prefLabel
Structural biology of the Bcl-2 family of proteins.
@ast
Structural biology of the Bcl-2 family of proteins.
@en
P1476
Structural biology of the Bcl-2 family of proteins.
@en
P2093
Andrew M Petros
Edward T Olejniczak
P356
10.1016/J.BBAMCR.2003.08.012
P407
P577
2004-03-01T00:00:00Z