Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis.
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CFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisPredicting CFTR activity with front-runner cystic fibrosis drugs.Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance.Hallmarks of therapeutic management of the cystic fibrosis functional landscape.From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants.A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTRCFTR founder mutation causes protein trafficking defects in Chinese patients with cystic fibrosis.Repairing the basic defect in cystic fibrosis - one approach is not enough.Searching for a cure for cystic fibrosis. A 25-year quest in a nutshell.Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators.Roadmap for an early gene therapy for cystic fibrosis airway disease.Strategies for the etiological therapy of cystic fibrosis.Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule.Nasospheroids permit measurements of CFTR-dependent fluid transport.Toward inclusive therapy with CFTR modulators: Progress and challenges.Transformative therapies for rare CFTR missense alleles.
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P2860
Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@ast
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@en
type
label
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@ast
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@en
prefLabel
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@ast
Measurements of Functional Res ...... d Therapy for Cystic Fibrosis.
@en
P2093
P2860
P50
P1433
P1476
Measurements of Functional Res ...... ed Therapy for Cystic Fibrosis
@en
P2093
Amparo Solé
Inna Uliyakina
Juan Pastor
Karina Mendes
P2860
P304
P356
10.1016/J.EBIOM.2014.12.005
P577
2014-12-17T00:00:00Z