KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.
about
KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin.Essential role of retinoblastoma protein in mammalian hair cell development and hearing.Ion channel gene expression in the inner earCharacterization of KCNQ5/Q3 potassium channels expressed in mammalian cellsInactivation as a new regulatory mechanism for neuronal Kv7 channelsKCNQ potassium channels in sensory system and neural circuitsNeuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and PitfallsMice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organsStructure of a Ca2+/CaM:Kv7.4 (KCNQ4) B-Helix Complex Provides Insight into M Current ModulationKCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currentsFunctional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytesThe acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytesK(V)7/KCNQ channels are functionally expressed in oligodendrocyte progenitor cellsMice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness.Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing lossFrom the ultrasonic to the infrared: molecular evolution and the sensory biology of bats.The voltage-gated potassium channel subfamily KQT member 4 (KCNQ4) displays parallel evolution in echolocating bats.Parallel evolution of KCNQ4 in echolocating batsIdentification of novel mutations in the KCNQ4 gene of patients with nonsyndromic deafness from Taiwan.Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids.Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitusKCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearingAge-related changes in the relationship between auditory brainstem responses and envelope-following responses.Potassium ion movement in the inner ear: insights from genetic disease and mouse modelsLoss of auditory activity modifies the location of potassium channel KCNQ5 in auditory brainstem neuronsGenetics of auditory mechano-electrical transduction.Recognition and control of the progression of age-related hearing loss.Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear.An in vitro model system to study gene therapy in the human inner ear.Dominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner earGene transfer in human vestibular epithelia and the prospects for inner ear gene therapy.Pathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus.Genetics of hearing loss: focus on DFNA2.A computational model of inferior colliculus responses to amplitude modulated sounds in young and aged rats.Function and mechanism of axonal targeting of voltage-sensitive potassium channels.Molecular biology of hearing.Myosin light-chain kinase is necessary for membrane homeostasis in cochlear inner hair cells.Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment.KCNQ5 channels control resting properties and release probability of a synapse
P2860
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P2860
KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@ast
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@en
type
label
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@ast
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@en
prefLabel
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@ast
KCNQ4, a K+ channel mutated in ...... the central auditory pathway.
@en
P2093
P2860
P50
P356
P1476
KCNQ4, a K+ channel mutated in ...... d the central auditory pathway
@en
P2093
J P Hardelin
M Schweizer
T Kharkovets
P2860
P304
P356
10.1073/PNAS.97.8.4333
P407
P577
2000-04-01T00:00:00Z