Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons - Wikidata - awgldk - TriplyDB

Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

http://www.wikidata.org/entity/Q35688476

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Antibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and function β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons.6'-Guanidinonaltrindole (6'-GNTI) is a G protein-biased κ-opioid receptor agonist that inhibits arrestin recruitment.Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10.Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain.In vivo opioid receptor heteromerization: where do we stand?Dual regulation of δ-opioid receptor function by arachidonic acid metabolites in rat peripheral sensory neurons.Native serotonin 5-HT2C receptors are expressed as homodimers on the apical surface of choroid plexus epithelial cells Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons.Molecular Pharmacology of δ-Opioid Receptors.Receptor and channel heteromers as pain targets.Bioactive conformations of two seminal delta opioid receptor penta-peptides inferred from free-energy profiles G Protein-Coupled Receptor Heteromers.Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer.Disease-specific heteromerization of G-protein-coupled receptors that target drugs of abuse G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.G-protein-coupled heteromers: regulation in disease Grand opening of structure-guided design for novel opioids.Dynorphin A analogs for the treatment of chronic neuropathic pain.Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future Therapeutics.Constitutive Desensitization of Opioid Receptors in Peripheral Sensory Neurons.Long-Term Reduction of Kappa Opioid Receptor Function by the Biased Ligand, Norbinaltorphimine, Requires c-Jun N-Terminal Kinase Activity and New Protein Synthesis in Peripheral Sensory Neurons.Identification of a signaling cascade that maintains constitutive δ-opioid receptor incompetence in peripheral sensory neurons.Heteromers of μ opioid and dopamine D1 receptors modulate opioid-induced locomotor sensitization in a dopamine-independent manner.Detection of Receptor Heteromerization Using In Situ Proximity Ligation Assay.Allosterism within delta opioid-kappa opioid receptor heteromers in peripheral sensory neurons: Regulation of kappa opioid agonist efficacy.Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

http://www.wikidata.org/entity/Q35688476

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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name

Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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type

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Molecular Pharmacology

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Allosteric interactions between δ and κ opioid receptors in peripheral sensory neurons

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Achla Gupta

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Blaine A McGuire

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Ivone Gomes

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Kelly A Berg

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Kenneth M Hargreaves

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Lakshmi A Devi

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Matthew P Rowan

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Michelle Silva

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Philip S Portoghese

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Teresa A Sanchez

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P2860

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

G-protein-coupled receptor heterodimerization modulates receptor function

Allostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapes

Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716

II - Prostaglandin hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists

Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

Integrins regulate opioid receptor signaling in trigeminal ganglion neurons

Bradykinin-induced functional competence and trafficking of the delta-opioid receptor in trigeminal nociceptors

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers

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10.1124/MOL.111.072702

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2

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81

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