Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
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Drugs under preclinical and clinical study for treatment of acute and chronic lymphoblastic leukemiaRegulation of Bim in Health and DiseasePrediction of gene-based drug indications using compendia of public gene expression data and PubMed abstracts.Glucocorticoid receptor β stimulates Akt1 growth pathway by attenuation of PTEN.PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemiaInhibition of autophagy overcomes glucocorticoid resistance in lymphoid malignant cells.Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemiaModulation of Glucocorticoid Resistance in Pediatric T-cell Acute Lymphoblastic Leukemia by Increasing BIM Expression with the PI3K/mTOR Inhibitor BEZ235MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesNK/T-cell lymphomas in childrenPharmacogenomic considerations of xenograft mouse models of acute leukemia.New Approaches to Target T-ALL.Targeting PI3K/AKT/mTOR network for treatment of leukemia.Personalization of dexamethasone therapy in childhood acute lymphoblastic leukaemia.Epothilone B induces apoptosis and enhances apoptotic effects of ABT-737 on human cancer cells via PI3K/AKT/mTOR pathway.Evodiamine induces apoptosis and enhances apoptotic effects of erlotinib in wild-type EGFR NSCLC cells via S6K1-mediated Mcl-1 inhibition.Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosis in vitro and in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase sGeneration of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice.Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia.Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.Differential expression of GAS5 in rapamycin-induced reversion of glucocorticoid resistance.Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An UpdateBiological Aspects of mTOR in Leukemia
P2860
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P2860
Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@ast
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@en
type
label
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@ast
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@en
prefLabel
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@ast
Synergistic activity of rapamy ...... ll-cycle arrest and apoptosis.
@en
P2093
P2860
P4510
P921
P1433
P1476
Synergistic activity of rapamy ...... ell-cycle arrest and apoptosis
@en
P2093
Chong Zhang
Connor P Hall
Daniel R Webster
Taylor Z Chen
Yong-Ku Ryu
P2860
P304
P356
10.1016/J.LEUKRES.2011.10.022
P50
P577
2011-12-03T00:00:00Z