PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. - Wikidata - awgldk - TriplyDB

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

http://www.wikidata.org/entity/Q35691132

about

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis Mitochondrial Quality Control and Muscle Mass Maintenance Road to exercise mimetics: targeting nuclear receptors in skeletal muscle Regulation of metabolism: the circadian clock dictates the time Nuclear receptor coregulators: modulators of pathology and therapeutic targets Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond Transcriptional integration of mitochondrial biogenesis PGC-1 proteins and heart failure Evolving roles of circadian rhythms in liver homeostasis and pathology Role of mitochondria in nonalcoholic fatty liver disease Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α Circadian influences on dopamine circuits of the brain: regulation of striatal rhythms of clock gene expression and implications for psychopathology and disease Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism Adipose Clocks: Burning the Midnight Oil Circadian regulation of metabolism Endocrine-disrupting chemicals and fatty liver disease.Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.IL-15 overexpression promotes endurance, oxidative energy metabolism, and muscle PPARδ, SIRT1, PGC-1α, and PGC-1β expression in male mice.Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection.Nuclear receptors, mitochondria and lipid metabolism Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.The role of PGC-1 coactivators in aging skeletal muscle and heart.Coactivators in PPAR-Regulated Gene Expression Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network Transcriptome profiles link environmental variation and physiological response of Mytilus californianus between Pacific tides.NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype Metabolism and the circadian clock converge.Nuclear receptors rock around the clock Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2.Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems.Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding.The PGC-1 cascade as a therapeutic target for heart failure PGC-1 coactivators in the control of energy metabolism.

P2860

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P2860

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

http://www.wikidata.org/entity/Q35691132

description

2007 nî lūn-bûn

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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name

PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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type

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PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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P356

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

PGC-1beta controls mitochondri ...... enesis, and hepatic steatosis.

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P2093

Isaac R Mehl

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Junichiro Sonoda

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Ling-Wa Chong

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Russell R Nofsinger

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P2860

The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha

Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

A gene atlas of the mouse and human protein-encoding transcriptomes

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

The nuclear receptor superfamily: the second decade

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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12

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104

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Ronald M. Evans

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P5875

6447573

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P698

17360356

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P921

circadian rhythm

P932

1829290

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