Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs. - Wikidata - awgldk - TriplyDB

Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

http://www.wikidata.org/entity/Q35694142

about

Boron chemicals in diagnosis and therapeutics Looking beneath the surface to determine what makes DNA damage deleterious Reactive-Oxygen-Species-Responsive Drug Delivery Systems: Promises and Challenges Synthesis of cross-linked DNA containing oxidized abasic site analogues.Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes.Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreductively activated, hypoxia-selective DNA-oxidizing agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications.Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species A new strategy for site-specific alkylation of DNA using oligonucleotides containing an abasic site and alkylating probes.Catalytic enantioselective alkene aminohalogenation/cyclization involving atom transfer.Exploring hydrogen peroxide responsive thiazolidinone-based prodrugs.Novel oxidatively activated agents modify DNA and are enhanced by ercc1 silencing.ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block.Novel ROS-activated agents utilize a tethered amine to selectively target acute myeloid leukemia.Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.In vivo targeting of hydrogen peroxide by activatable cell-penetrating peptides.Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition The leaving group strongly affects H₂O₂-induced DNA cross-linking by arylboronates.Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell Experimental approaches to identify cellular G-quadruplex structures and functions.Reaction-based small-molecule fluorescent probes for chemoselective bioimaging G-quadruplexes incorporating modified constituents: a review.Self-immolative spacers: kinetic aspects, structure-property relationships, and applications.Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery.Overcoming the Achilles' heel of photodynamic therapy.Photo-triggered fluorescent theranostic prodrugs as DNA alkylating agents for mechlorethamine release and spatiotemporal monitoring.On The Latest Three-Stage Development of Nanomedicines based on Upconversion Nanoparticles.Bioconjugation - using selective chemistry to enhance the properties of proteins and peptides as therapeutics and carriers.Design of a hydrogen peroxide-activatable agent that specifically targets cancer cells.Reactive Oxygen, Nitrogen, and Sulfur Species (RONSS)-Responsive Polymersomes for Triggered Drug Release.Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy.Fluoride as an inducible DNA cross-linking agent for new antitumor prodrug.ROS-activated anticancer prodrugs: a new strategy for tumor-specific damage.Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells.Aromatic nitrogen mustard-based prodrugs: activity, selectivity, and the mechanism of DNA cross-linking.A Tumor-Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers.Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments.Nanocarriers with multi-locked DNA valves targeting intracellular tumor-related mRNAs for controlled drug release.A 'photorelease, catch and photorelease' strategy for bioconjugation utilizing a p-hydroxyphenacyl group.

P2860

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P2860

Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

http://www.wikidata.org/entity/Q35694142

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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name

Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

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Journal of the American Chemical Society

P1476

Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.

@en

P2093

Kumudha Balakrishnan

http://www.w3.org/2001/XMLSchema#string

Varsha Gandhi

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Xiaohua Peng

http://www.w3.org/2001/XMLSchema#string

Yunyan Kuang

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P2860

The reaction of mono- and di-functional alkylating agents with nucleic acids

Formation and repair of interstrand cross-links in DNA

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Production of large amounts of hydrogen peroxide by human tumor cells

Binol quinone methides as bisalkylating and DNA cross-linking agents.

Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.

A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor

A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC)

Persistent oxidative stress in cancer.

DNA interstrand cross-link formation initiated by reaction between singlet oxygen and a modified nucleotide

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19278-19281

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scholarly article

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10.1021/JA2073824

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48

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133

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2011-11-10T00:00:00Z

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51754937

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22035519

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