The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling.
about
A drug-sensitive genetic network masks fungi from the immune systemCell wall assembly in Saccharomyces cerevisiaeControl of the C. albicans cell wall damage response by transcriptional regulator Cas5.pH signaling in human fungal pathogens: a new target for antifungal strategiesTranscriptional response of Saccharomyces cerevisiae to the plasma membrane-perturbing compound chitosan.A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).NCW2, a Gene Involved in the Tolerance to Polyhexamethylene Biguanide (PHMB), May Help in the Organisation of β-1,3-Glucan Structure of Saccharomyces cerevisiae Cell Wall.The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis.The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiaePKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurinSystematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genesMetal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and MorphogenesisNPFXD-mediated endocytosis is required for polarity and function of a yeast cell wall stress sensor.Highly Dynamic and Specific Phosphatidylinositol 4,5-Bisphosphate, Septin, and Cell Wall Integrity Pathway Responses Correlate with Caspofungin Activity against Candida albicans.Stimulation of chitin synthesis rescues Candida albicans from echinocandins.Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivityA role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus.Inferring Transcriptional Interactions by the Optimal Integration of ChIP-chip and Knock-out DataThe antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans.A novel connection between the Cell Wall Integrity and the PKA pathways regulates cell wall stress response in yeast.The Aspergillus giganteus antifungal protein AFPNN5353 activates the cell wall integrity pathway and perturbs calcium homeostasis.The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans.Chitin synthesis and fungal pathogenesis.Regulatory circuitry governing fungal development, drug resistance, and disease.Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type II-deficiency (myo1Δ).Elucidating drug resistance in human fungal pathogens.Involvement of protein kinase C in the suppression of apoptosis and in polarity establishment in Aspergillus nidulans under conditions of heat stress.Disruption of the transcriptional regulator Cas5 results in enhanced killing of Candida albicans by FluconazoleMultiple signaling pathways regulate yeast cell death during the response to mating pheromones.Plant-derived antifungal agent poacic acid targets β-1,3-glucan.Interface of Candida albicans biofilm matrix-associated drug resistance and cell wall integrity regulation.Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.Elevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo.Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature.Augmenting the Activity of Monoterpenoid Phenols against Fungal Pathogens Using 2-Hydroxy-4-methoxybenzaldehyde that Target Cell Wall Integrity.Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans.Regulation of the Candida albicans cell wall damage response by transcription factor Sko1 and PAS kinase Psk1The pharmacology and clinical use of caspofungin.Resistance to echinocandin-class antifungal drugs.
P2860
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P2860
The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The yeast protein kinase C cel ...... ated protein kinase signaling.
@ast
The yeast protein kinase C cel ...... ated protein kinase signaling.
@en
type
label
The yeast protein kinase C cel ...... ated protein kinase signaling.
@ast
The yeast protein kinase C cel ...... ated protein kinase signaling.
@en
prefLabel
The yeast protein kinase C cel ...... ated protein kinase signaling.
@ast
The yeast protein kinase C cel ...... ated protein kinase signaling.
@en
P2093
P2860
P1433
P1476
The yeast protein kinase C cel ...... ated protein kinase signaling.
@en
P2093
Christoph Schüller
Cristina Reinoso-Martín
Karl Kuchler
Manuela Schuetzer-Muehlbauer
P2860
P304
P356
10.1128/EC.2.6.1200-1210.2003
P577
2003-12-01T00:00:00Z