Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects
about
Genome-scale CRISPR pooled screens.Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.Systematic morphological profiling of human gene and allele function via Cell Painting.Data-analysis strategies for image-based cell profiling.Applications of CRISPR genome editing technology in drug target identification and validation.RIsearch2: suffix array-based large-scale prediction of RNA-RNA interactions and siRNA off-targets.High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.Profiling DNA damage response following mitotic perturbations.Evaluation and control of miRNA-like off-target repression for RNA interference.Am I ready for CRISPR? A user's guide to genetic screens.Large-scale image-based profiling of single-cell phenotypes in arrayed CRISPR-Cas9 gene perturbation screens.Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map.RNA Interference (RNAi) Screening in Drosophila.Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition
P2860
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P2860
Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@ast
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@en
type
label
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@ast
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@en
prefLabel
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@ast
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@en
P2093
P2860
P1433
P1476
Morphological Profiles of RNAi ...... but Dominated by Seed Effects
@en
P2093
David E Root
Federica Piccioni
John G Doench
Mark-Anthony Bray
Shantanu Singh
Vebjorn Ljosa
Xiaoyun Wu
P2860
P304
P356
10.1371/JOURNAL.PONE.0131370
P407
P577
2015-07-21T00:00:00Z