Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction. - Wikidata - awgldk - TriplyDB

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.

http://www.wikidata.org/entity/Q35709003

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Vaccines: from empirical development to rational design Can follicular helper T cells be targeted to improve vaccine efficacy?The Use of Synthetic Carriers in Malaria Vaccine Design Cell Membrane-Coated Nanoparticles As an Emerging Antibacterial Vaccine Platform Biomimetic and synthetic interfaces to tune immune responses Materials based tumor immunotherapy vaccines Advances in structure-based vaccine design Particulate delivery systems for vaccination against bioterrorism agents and emerging infectious pathogens CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines Combining cationic liposomal delivery with MPL-TDM for cysteine protease cocktail vaccination against Leishmania donovani: evidence for antigen synergy and protection Synthetic Nanoparticles for Vaccines and Immunotherapy A Little Help From the Follicles: Understanding the Germinal Center Response to Human Immunodeficiency Virus 1 Infection and Prophylactic Vaccines.Activation of the RIG-I pathway during influenza vaccination enhances the germinal center reaction, promotes T follicular helper cell induction, and provides a dose-sparing effect and protective immunity.AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice.HIV-1 vaccines: challenges and new perspectives Combinatorial Delivery of Dual and Triple TLR Agonists via Polymeric Pathogen-like Particles Synergistically Enhances Innate and Adaptive Immune Responses.The role of extracellular vesicles in malaria biology and pathogenesis.CD4+CXCR5+ follicular helper T cells in salivary gland promote B cells maturation in patients with primary Sjogren's syndrome Nonneutralizing functional antibodies: a new "old" paradigm for HIV vaccines Design of lipid nanocapsule delivery vehicles for multivalent display of recombinant Env trimers in HIV vaccination Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine Nanotoxoid Vaccines Biomaterials for nanoparticle vaccine delivery systems.Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles.Theranostic nanoparticles carrying doxorubicin attenuate targeting ligand specific antibody responses following systemic delivery.IFN-α as an Adjuvant for Adenovirus-Vectored FMDV Subunit Vaccine through Improving the Generation of T Follicular Helper Cells Inhibition of increased circulating Tfh cell by anti-CD20 monoclonal antibody in patients with type 1 diabetes.Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation.Modulating antibacterial immunity via bacterial membrane-coated nanoparticles Reorienting our view of particle-based adjuvants for subunit vaccines.Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses.Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8+ T cell responses after nanoparticle vaccination.Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity.Supramolecular peptide vaccines: tuning adaptive immunity.Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine.Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery.Particle-based platforms for malaria vaccines.

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P2860

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.

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Adrienne V Li

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Anjali Yadava

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Christian F Ockenhouse

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Darrell J Irvine

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Heikyung Suh

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James J Moon

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P2860

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

Vivax malaria: neglected and not benign

Programming the magnitude and persistence of antibody responses with innate immunity.

Low immunogenicity of a Plasmodium vivax circumsporozoite protein epitope bound by a protective monoclonal antibody.

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses.

A novel chimeric Plasmodium vivax circumsporozoite protein induces biologically functional antibodies that recognize both VK210 and VK247 sporozoites.

Antigen-specific memory B cell development.

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.

The development of the RTS,S malaria vaccine candidate: challenges and lessons.

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