An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development.
about
Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter.Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript.Sequences closely related to an immunoglobulin gene promoter/enhancer element occur also upstream of other eukaryotic and of prokaryotic genes.A conserved heptamer upstream of the IgH promoter region octamer can be the site of a coordinate protein-DNA interaction.Structure of the 5' ends of immunoglobulin genes: a novel conserved sequenceBoundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family.Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation.Novel protein-DNA interactions associated with increased immunoglobulin transcription in response to antigen plus interleukin-5.A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.Fine mapping of an immunoglobulin gene activatorCharacterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.Clonal proliferation of murine lymphohemopoietic progenitors in culture.Mutational analysis of the immunoglobulin heavy chain promoter region.Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.Somatic mutation in constant regions of mouse lambda 1 light chainsFunctional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cellsComplete nucleotide sequences of three VH genes in Caiman, a phylogenetically ancient reptile: evolutionary diversification in coding segments and variation in the structure and organization of recombination elementsEvidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment.Regulatory elements involved in the bidirectional activity of an immunoglobulin promoterTranslocation affects normal c-myc promoter usage and activates fifteen cryptic c-myc transcription starts in plasmacytoma M603.Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse.Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.Comparison of somatic mutation frequency among immunoglobulin genes.
P2860
Q34359857-DF3B2462-C07B-42B1-BDBC-3A508EC52BBFQ35048825-2A96E3F6-053D-4941-B12F-6E54FC958F71Q35057079-229130A6-00F5-4269-BED6-2B3DA28029AEQ36009942-432F778F-1AE5-451F-BB90-A11C6A9696FFQ36258756-48CAF277-7C65-4035-B5A8-8FD0FA4F1D55Q36354162-58664483-9B3E-4750-A0E7-8F8D985893D0Q36491050-BB02B288-F944-4AED-A1A1-71FF293FF592Q36688566-937F7F54-8FC8-4DB6-8DC2-2F3756D75397Q36737517-B9C316AF-0D81-4688-A906-DFBDBEF9DD5CQ36802885-1F7EEC3F-54D9-439B-BA15-3F6C9F7DCDEFQ36945043-9FEFCA1D-3059-49B3-9DA3-BF5F8392A80EQ36981842-B7FBC357-01A2-4558-A09C-57DCE3A34225Q37084463-F52CB6CE-19EA-4856-9527-52BCC28D246FQ37411997-756F206C-8A2C-4071-9727-5F791F572F0BQ37576261-52DA67C8-ADB4-42CE-B706-4958A6CFCCC9Q37591443-ABEF423D-007A-4091-AFF4-A053B752AC38Q37618235-0DC64A08-0A1B-4FCC-BC92-A65FC1BBFD68Q37677014-0249E936-8535-496C-87E8-8C9B72FC4C16Q39576391-33526B12-760C-47DA-848C-3A1E53F0A8EAQ40447847-D5783188-A8C2-4945-973E-CC6727D9FEA1Q40463180-F951E936-A1E2-4D6E-BCB7-66CA866FDFF2Q41359348-0EB37420-47C2-4FF7-A769-A01703E803C9Q41459613-AB5EB524-22B6-436E-A742-4DB2FC6D80B7Q42248453-23B5B526-3CAF-4207-8758-86154749DC3A
P2860
An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
An immunoglobulin promoter reg ...... ion during B-cell development.
@ast
An immunoglobulin promoter reg ...... ion during B-cell development.
@en
type
label
An immunoglobulin promoter reg ...... ion during B-cell development.
@ast
An immunoglobulin promoter reg ...... ion during B-cell development.
@en
prefLabel
An immunoglobulin promoter reg ...... ion during B-cell development.
@ast
An immunoglobulin promoter reg ...... ion during B-cell development.
@en
P2093
P2860
P356
P1476
An immunoglobulin promoter reg ...... ion during B-cell development.
@en
P2093
Berenson J
Goverman J
P2860
P304
P356
10.1093/NAR/10.23.7731
P407
P577
1982-12-01T00:00:00Z