Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.
about
Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assayLarge Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseStructure of Rhomboid Protease in Complex with β-Lactam Inhibitors Defines the S2′ CavityConformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S′ SubsitesProteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate AffinityAllosteric regulation of rhomboid intramembrane proteolysisMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Structure and mechanism of rhomboid proteaseSubstrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structuresA new class of rhomboid protease inhibitors discovered by activity-based fluorescence polarizationBiochemical and structural insights into intramembrane metalloprotease mechanisms.Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-σKStructural and mechanistic principles of intramembrane proteolysis--lessons from rhomboids.Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid ProteolysisAlternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4.Intramembrane proteases as drug targets.Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease.Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases.
P2860
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P2860
Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@ast
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@en
type
label
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@ast
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@en
prefLabel
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@ast
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@en
P2860
P356
P1476
Catalytic mechanism of rhomboi ...... diisopropyl fluorophosphonate.
@en
P2860
P304
P356
10.1074/JBC.M111.310482
P407
P577
2011-11-29T00:00:00Z