5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.
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Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATMMesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity.In vivo effects of mesalazine or E. coli Nissle 1917 on microsatellite instability in ulcerative colitisAntioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells.Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer.Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre miceCost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylates.Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis.Colorectal cancer chemoprevention by mesalazine and its derivatives.Mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDs) and mesalazine in the chemoprevention of colorectal cancer.Chemoprevention of colorectal cancer in inflammatory bowel disease.Systematic review with meta-analysis: use of 5-aminosalicylates and risk of colorectal neoplasia in patients with inflammatory bowel disease.Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study.Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrestMesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.Molecular basis of the potential of mesalazine to prevent colorectal cancer.Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells.5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes.DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer.5-Aminosalicylic Acid Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats by Increasing the Expression of Nur77.
P2860
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P2860
5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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2006年论文
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2006年论文
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name
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@ast
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@en
type
label
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@ast
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@en
prefLabel
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@ast
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@en
P2093
P2860
P1433
P1476
5-ASA affects cell cycle progr ...... ting a replication checkpoint.
@en
P2093
Christoph Campregher
Christoph Gasche
John M Fortune
M Gloria Luciani
Thomas A Kunkel
P2860
P304
P356
10.1053/J.GASTRO.2006.10.016
P407
P577
2006-10-12T00:00:00Z