Pharmacokinetically stabilized cystine knot peptides that bind alpha-v-beta-6 integrin with single-digit nanomolar affinities for detection of pancreatic cancer
about
Molecular imaging of integrin αvβ6 expression in living subjects.Combining in Vitro Diagnostics with in Vivo Imaging for Earlier Detection of Pancreatic Ductal Adenocarcinoma: Challenges and Solutions.A Cystine Knot Peptide Targeting Integrin αvβ6 for Photoacoustic and Fluorescence Imaging of Tumors in Living Subjects.Dimerization of a phage-display selected peptide for imaging of αvβ6- integrin: two approaches to the multivalent effect.18F-fluorobenzoate-labeled cystine knot peptides for PET imaging of integrin αvβ6.Dynamic scenario of membrane binding process of kalata b1Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imagingThe Effect of Bi-Terminal PEGylation of an Integrin αvβ₆-Targeted ¹⁸F Peptide on Pharmacokinetics and Tumor Uptake.Tumor-targeting peptides from combinatorial libraries.Designed hydrophilic and charge mutations of the fibronectin domain: towards tailored protein biodistribution.Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display.How fibrosis influences imaging and surgical decisions in pancreatic cancer.Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration.Alternative Non-Antibody Protein Scaffolds for Molecular Imaging of Cancer99mTc-labeled cystine knot peptide targeting integrin αvβ6 for tumor SPECT imaging.The role of stroma in pancreatic cancer: diagnostic and therapeutic implications.Joseph Rudinger memorial lecture: discovery and applications of cyclotides.Cyclotides as grafting frameworks for protein engineering and drug design applications.Tumor Targeting via Integrin Ligands.PET radiopharmaceuticals for imaging integrin expression: tracers in clinical studies and recent developments.Cystine-knot peptides: emerging tools for cancer imaging and therapy.Strategies to stabilize cell penetrating peptides for in vivo applications.Plant cystine-knot peptides: pharmacological perspectives.64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor.Discovery, structure, function, and applications of cyclotides: circular proteins from plants.Synthetic and natural consensus design for engineering charge within an affibody targeting epidermal growth factor receptor.Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma.Exploring the Role of RGD-Recognizing Integrins in Cancer.A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display.Thy1-Targeted Microbubbles for Ultrasound Molecular Imaging of Pancreatic Ductal Adenocarcinoma.Protein biomarkers on tissue as imaged via MALDI mass spectrometry: A systematic approach to study the limits of detection.Synthetic Cystine-Knot Miniproteins - Valuable Scaffolds for Polypeptide Engineering.Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding.
P2860
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P2860
Pharmacokinetically stabilized cystine knot peptides that bind alpha-v-beta-6 integrin with single-digit nanomolar affinities for detection of pancreatic cancer
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@ast
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@en
type
label
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@ast
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@en
prefLabel
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@ast
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@en
P2093
P2860
P1476
Pharmacokinetically stabilized ...... detection of pancreatic cancer
@en
P2093
Ataya Sathirachinda
Benjamin J Hackel
Courtney Z Chuang
Marybeth A Pysz
Richard H Kimura
Robert Teed
Sanjiv S Gambhir
P2860
P304
P356
10.1158/1078-0432.CCR-11-1116
P407
P577
2011-12-15T00:00:00Z