Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.

about

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.A plasma proteolysis pathway comprising blood coagulation proteases PEPD is a pivotal regulator of p53 tumor suppressor.

P2860

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P2860

Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.

Item

http://www.wikidata.org/entity/Q35733827

description

2015 nî lūn-bûn

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2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@ast

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@en

type

Item

label

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@ast

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@en

prefLabel

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@ast

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@en

P1476

Inhibition of ERBB2-overexpres ...... Enzymatically Inactive Mutant.

@en

P2093

Arup Bhattacharya

http://www.w3.org/2001/XMLSchema#string

Lu Yang

http://www.w3.org/2001/XMLSchema#string

Yun Li

http://www.w3.org/2001/XMLSchema#string

P2860

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner

Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab

Expression and molecular analysis of mutations in prolidase deficiency

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

Targeted therapy for HER2 positive breast cancer

Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

P304

396-405

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P31

scholarly article

P356

10.1016/J.EBIOM.2015.03.016

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Yuesheng Zhang

P577

2015-05-01T00:00:00Z

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P5875

274095725

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P698

26086037

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P921

overexpression

P932

4465122

http://www.w3.org/2001/XMLSchema#string

Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.

about

P2860

P2860

Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932