The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
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Cytosolic Innate Immune Sensing and Signaling upon InfectionVersatile myeloid cell subsets contribute to tuberculosis-associated inflammationCD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis InfectionThe ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10The ubiquitin system: a critical regulator of innate immunity and pathogen-host interactionsDNA sensor cGAS-mediated immune recognitionProtection and pathology in TB: learning from the zebrafish modelGlutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunityCrosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity.Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection.Getting "Inside" Type I IFNs: Type I IFNs in Intracellular Bacterial InfectionsDNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota.ESX-1 exploits type I IFN-signalling to promote a regulatory macrophage phenotype refractory to IFNγ-mediated autophagy and growth restriction of intracellular mycobacteria.Inhibition of cGAS DNA Sensing by a Herpesvirus Virion ProteinThe Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent.Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseasesSENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.Mycobacterial infection induces a specific human innate immune response.Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulenceAutophagy-Related Proteins Target Ubiquitin-Free Mycobacterial Compartment to Promote Killing in MacrophagesMycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivoA Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection.Strategies Used by Bacteria to Grow in MacrophagesCharacterization of differential pore-forming activities of ESAT-6 proteins from Mycobacterium tuberculosis and Mycobacterium smegmatisMechanism of ESAT-6 membrane interaction and its roles in pathogenesis of Mycobacterium tuberculosis.EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5.Cyclic di-AMP Released from Staphylococcus aureus Biofilm Induces a Macrophage Type I Interferon Response.Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses.EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection.EssD, a Nuclease Effector of the Staphylococcus aureus ESS PathwayClash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses.AIM2 inhibits autophagy and IFN-β production during M. bovis infectionDecreased expression of STING predicts poor prognosis in patients with gastric cancer.Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases.The Emerging Roles of STING in Bacterial Infections.Absence of Specific Chlamydia trachomatis Inclusion Membrane Proteins Triggers Premature Inclusion Membrane Lysis and Host Cell Death.
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P2860
The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@ast
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@en
type
label
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@ast
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@en
prefLabel
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@ast
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@en
P2093
P2860
P1433
P1476
The Cytosolic Sensor cGAS Dete ...... rferons and Activate Autophagy
@en
P2093
Christina L Stallings
Donna A MacDuff
Elie J Diner
Herbert W Virgin
Jeffery S Cox
Joanna Olivas
Robert O Watson
Russell E Vance
P2860
P304
P356
10.1016/J.CHOM.2015.05.004
P577
2015-06-02T00:00:00Z