Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules.
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Chemicals as the Sole Transformers of Cell FateChemically Induced Reprogramming of Somatic Cells to Pluripotent Stem Cells and Neural CellsUnderstanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron ReprogrammingA potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neuronsReprogramming cell fates by small molecules.Sequential EMT-MET induces neuronal conversion through Sox2.Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds.Stem cells: fast track to neurons.Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogrammingSmall molecules increase direct neural conversion of human fibroblasts.Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors.Transient CREB-mediated transcription is key in direct neuronal reprogramming.Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons.REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo.Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications.Concise Review: Progress and Challenges in Using Human Stem Cells for Biological and Therapeutics Discovery: Neuropsychiatric Disorders.Tissue Engineering and Regenerative Medicine 2015: A Year in ReviewMeta-Analysis of EMT Datasets Reveals Different Types of EMT.Physiological, pathological, and engineered cell identity reprogramming in the central nervous system.Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin.Induced dopaminergic neurons: A new promise for Parkinson's disease.Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models.Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neuronsDirect Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules.Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts.New approaches for direct conversion of patient fibroblasts into neural cells.Small molecules for reprogramming and transdifferentiation.Neuroregeneration versus neurodegeneration: toward a paradigm shift in Alzheimer's disease drug discovery.Biophysical regulation of cell reprogramming.Cell fate modification toward the hepatic lineage by extrinsic factors.Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes.Human stem cell modeling in neurofibromatosis type 1 (NF1).Recent Progress in Cell Reprogramming Technology for Cell Transplantation Therapy.An update on stem cell biology and engineering for brain development.Direct Conversion of Somatic Cells into Induced Neurons.Studying human disease using human neurons.Common Gene Expression Patterns in the Generation of Induced Neurons From Fibroblasts.
P2860
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P2860
Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@ast
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@en
type
label
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@ast
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@en
prefLabel
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@ast
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@en
P2093
P1433
P1476
Direct Conversion of Normal an ...... onal Cells by Small Molecules.
@en
P2093
Beisha Tang
Binlong Qiu
Gangcai Xie
Hanzhi Zhao
Longfei Gao
Qinying Wang
P304
P356
10.1016/J.STEM.2015.07.006
P407
P577
2015-08-01T00:00:00Z