R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants - Wikidata - awgldk - TriplyDB

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

http://www.wikidata.org/entity/Q35740611

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Out of balance: R-loops in human disease Breaking bad: R-loops and genome integrity Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability Sources of DNA double-strand breaks and models of recombinational DNA repair The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening R-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity.Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes.Biogenesis of RNA polymerases II and III requires the conserved GPN small GTPases in Saccharomyces cerevisiae.Cleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiae Genetic instability in budding and fission yeast-sources and mechanisms Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity Transcription-associated R-loop formation across the human FMR1 CGG-repeat region RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation.Mechanisms of genome instability induced by RNA-processing defects.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog.Synthetic lethality of cohesins with PARPs and replication fork mediators.Causes and consequences of replication stress.Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria Ribonuclease H2 in health and disease.The τCstF-64 polyadenylation protein controls genome expression in testis.Rescue from replication stress during mitosis.Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability Long noncoding RNAs promote transcriptional poising of inducible genes.BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.Regulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation.Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells.R-loops cause replication impairment and genome instability during meiosis Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1 Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork.The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.Alterations in polyadenylation and its implications for endocrine disease.

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

http://www.wikidata.org/entity/Q35740611

description

2012 nî lūn-bûn

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2012年の論文

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2012年论文

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name

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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type

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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prefLabel

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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Genes & Development

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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

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P2093

Irene Barrett

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Maria J Aristizabal

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Payal Sipahimalani

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Philip Hieter

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Sean W Minaker

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Yujia A Chan

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P2860

The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX

AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12)

Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent

The DNA-damage response in human biology and disease

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

Rad52 forms DNA repair and recombination centers during S phase.

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163-175

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10.1101/GAD.179721.111

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2

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26

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Peter C. Stirling

Michael S Kobor

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2012-01-01T00:00:00Z

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221779089

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22279048

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3273840

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