about
Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptorsGenetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction.Exploitation of the nicotinic anti-inflammatory pathway for the treatment of epithelial inflammatory diseases.Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays.α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats.Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.Emerging concepts: novel integration of in vivo approaches to localize the function of nicotinic receptors.Varenicline for smoking cessation.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.Ryanodine is a positive modulator of acetylcholine receptor gating in cochlear hair cells.Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function.Medications Development for the Treatment of Nicotine Dependence in Individuals with Schizophrenia.Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques.Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulationCellular responses to nicotinic receptor activation are decreased after prolonged exposure to galantamine in human neuroblastoma cells.Cotinine antagonizes the behavioral effects of nicotine exposure in the planarian Girardia tigrina.Positive allosteric modulation of alpha7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons.Overview of Electrophysiological Techniques.[³H]Chiba-1001(methyl-SSR180711) has low in vitro binding affinity and poor in vivo selectivity to nicotinic alpha-7 receptor in rodent brain.The Role of Halogen Bonding in Crystal Structures of 3-Halogeno Cytisine DerivativesThe Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an in Vitro Model of Alzheimer Disease
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Nicotinic acetylcholine receptors as drug targets.
@ast
Nicotinic acetylcholine receptors as drug targets.
@en
type
label
Nicotinic acetylcholine receptors as drug targets.
@ast
Nicotinic acetylcholine receptors as drug targets.
@en
prefLabel
Nicotinic acetylcholine receptors as drug targets.
@ast
Nicotinic acetylcholine receptors as drug targets.
@en
P356
P1476
Nicotinic acetylcholine receptors as drug targets.
@en
P2093
P304
P356
10.2174/1568007043482507
P577
2004-04-01T00:00:00Z