Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine.
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Drug repositioning approaches for the discovery of new therapeutics for Alzheimer's diseaseRelationship Between Antihypertensive Medications and Cognitive Impairment: Part II. Review of Physiology and Animal StudiesA Novel 1,4-Dihydropyridine Derivative Improves Spatial Learning and Memory and Modifies Brain Protein Expression in Wild Type and Transgenic APPSweDI MiceDendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neuronsAltered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob diseaseA novel design of a Phase III trial of isradipine in early Parkinson disease (STEADY-PD III).Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase.Bio-inspired voltage-dependent calcium channel blockersAPP as a Protective Factor in Acute Neuronal Insults.Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism.Pharmacokinetic properties of isradipine after single-dose and multiple-dose oral administration in Chinese volunteers: a randomized, open-label, parallel-group phase I study.Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammationConotoxins that confer therapeutic possibilities.L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca2+ channels.Regulation of voltage-dependent calcium channels by RGK proteins.The changing landscape of voltage-gated calcium channels in neurovascular disorders and in neurodegenerative diseasesDantrolene, a treatment for Alzheimer disease?A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25-35-impaired mouse cognitive function.Autophagy and Alzheimer's Disease.Perspectives for treating Alzheimer's disease: a review on promising pharmacological substances.Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.Review: Cav2.3 R-type Voltage-Gated Ca2+ Channels - Functional Implications in Convulsive and Non-convulsive Seizure Activity.Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation.Beta amyloid suppresses the expression of the vitamin d receptor gene and induces the expression of the vitamin d catabolic enzyme gene in hippocampal neurons.Ion channels in the regulation of autophagy.Memory-enhancing and brain protein expression-stimulating effects of novel calcium antagonist in Alzheimer's disease transgenic female mice.Dihydromyricetin ameliorates behavioral deficits and reverses neuropathology of transgenic mouse models of Alzheimer's disease.Parkinson's disease is associated with altered expression of CaV1 channels and calcium-binding proteins.Mental Health Wellness and Biofield Therapies: An Integrative Review.Protective effect of a calcium channel blocker "diltiazem" on aluminum chloride-induced dementia in mice.Type-1 astrocyte-like stem cells harboring Cacna1d gene deletion exhibit reduced proliferation and decreased neuronal fate choice.The Bridging Integrator 1 Gene Polymorphism rs744373 and the Risk of Alzheimer's Disease in Caucasian and Asian Populations: An Updated Meta-Analysis.Research Progress in the Pathogenesis of Alzheimer's DiseaseSynergism of antihypertensives and cholinesterase inhibitors in Alzheimer's diseaseSTIM1 deficiency is linked to Alzheimer's disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca entryExcitatory Dendritic Mitochondrial Calcium Toxicity: Implications for Parkinson's and Other Neurodegenerative Diseases
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P2860
Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Calcium channel blocking as a ...... ease: the case for isradipine.
@ast
Calcium channel blocking as a ...... ease: the case for isradipine.
@en
type
label
Calcium channel blocking as a ...... ease: the case for isradipine.
@ast
Calcium channel blocking as a ...... ease: the case for isradipine.
@en
prefLabel
Calcium channel blocking as a ...... ease: the case for isradipine.
@ast
Calcium channel blocking as a ...... ease: the case for isradipine.
@en
P2860
P1476
Calcium channel blocking as a ...... ease: the case for isradipine.
@en
P2093
Joseph F Quinn
Thimmappa S Anekonda
P2860
P304
P356
10.1016/J.BBADIS.2011.08.013
P407
P577
2011-09-08T00:00:00Z