Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome
about
Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastomaExpression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomasGenetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects.Where do we stand with hepatoblastoma? A review.p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19Prognostic value of hedgehog signal component expressions in hepatoblastoma patients.Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.Emerging gene-directed anti-tumor strategies against human hepatoblastoma.Current and future management strategies for relapsed or progressive hepatoblastoma.Gene expression profiling of human hepatoblastoma using archived formalin-fixed and paraffin-embedded tissues.Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.Adult hepatoblastoma: a review of 47 cases.Upregulated genes at 2q24 gains as candidate oncogenes in hepatoblastomas.Up-regulated expression of phospholipase C, β1 is associated with tumor cell proliferation and poor prognosis in hepatocellular carcinoma.Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma.Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.Whole-genome profiling of chromosomal aberrations in hepatoblastoma using high-density single-nucleotide polymorphism genotyping microarrays.Low expression of N-myc downstream-regulated gene 2 (NDRG2) correlates with poor prognosis in hepatoblastoma.Two novel in vitro human hepatoblastoma models, HepU1 and HepU2, are highly characteristic of fetal-embryonal differentiation in hepatoblastoma.Copy-number variations in hepatoblastoma associate with unique clinical features.Blocking the hedgehog pathway inhibits hepatoblastoma growth.Gain of chromosome 8q is associated with metastases and poor survival of patients with clear cell renal cell carcinoma.Prenatally detected trisomy 20 mosaicism.Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21.The correlation between gain of chromosome 8q and survival in patients with clear and papillary renal cell carcinoma.Patient-derived mouse xenografts from pediatric liver cancer predict tumor recurrence and advise clinical management.Long Non-Coding RNA SNHG6 as a Potential Biomarker for Hepatocellular Carcinoma.An 8-cM interstitial deletion on 4q21-q22 in DNA from an infant with hepatoblastoma overlaps with a commonly deleted region in adult liver cancers.Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex.The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients.Frequent increase of DNA copy number in the 2q24 chromosomal region and its association with a poor clinical outcome in hepatoblastoma: cytogenetic and comparative genomic hybridization analysis.
P2860
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P2860
Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Characterization of genomic al ...... as predictors of poor outcome
@ast
Characterization of genomic al ...... as predictors of poor outcome
@en
type
label
Characterization of genomic al ...... as predictors of poor outcome
@ast
Characterization of genomic al ...... as predictors of poor outcome
@en
prefLabel
Characterization of genomic al ...... as predictors of poor outcome
@ast
Characterization of genomic al ...... as predictors of poor outcome
@en
P2093
P2860
P1476
Characterization of genomic al ...... as predictors of poor outcome
@en
P2093
D von Schweinitz
P2860
P304
P356
10.1016/S0002-9440(10)64567-1
P407
P577
2000-08-01T00:00:00Z