Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice

Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice

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http://www.wikidata.org/entity/Q35747361
Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation.Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's diseaseDifferential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic aβ peptide aggregatesNeuropathological verisimilitude in animal models of Alzheimer's disease: key to elucidating neurodegenerative pathways and identifying new targets for drug discoveryPre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's diseaseInteractions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease.Basal forebrain cholinergic dysfunction in Alzheimer's disease--interrelationship with beta-amyloid, inflammation and neurotrophin signaling.Phenserine.The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases.Coexisting cholinergic and parahippocampal degeneration: a key to memory loss in dementia and a challenge for transgenic models?Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?Calcitonin gene-related peptide (CGRP): A novel target for Alzheimer's disease.Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway.
P2860

Stable beta-secretase activity and presynaptic cholinergic markers during progressive central nervous system amyloidogenesis in Tg2576 mice

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http://www.wikidata.org/entity/Q35747361
description
2002 nî lūn-bûn
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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2002年论文
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2002年论文
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name
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@ast
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@en
type
label
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@ast
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@en
prefLabel
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@ast
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@en
P1433
P1476
P2093
P2860
P304
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P356
P407
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P932
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P1433
P1476
Stable beta-secretase activity ...... amyloidogenesis in Tg2576 mice
@en
P2093
P2860
P304
P31
P356
10.1016/S0002-9440(10)64893-6
P407
P433
P478
P577
P698
P932