Age-related somatic structural changes in the nuclear genome of human blood cells. - Wikidata - awgldk - TriplyDB

Age-related somatic structural changes in the nuclear genome of human blood cells.

Age-related somatic structural changes in the nuclear genome of human blood cells.

http://www.wikidata.org/entity/Q35748382

about

Detectable clonal mosaicism and its relationship to aging and cancer Characterization of large structural genetic mosaicism in human autosome Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome New insights into the generation and role of de novo mutations in health and disease The hallmarks of aging Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer Detectable clonal mosaicism from birth to old age and its relationship to cancer Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence Age-related mutations associated with clonal hematopoietic expansion and malignancies Ultra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samples Mosaic copy number variation in schizophrenia Assessment of megabase-scale somatic copy number variation using single-cell sequencing Somatic mosaicism for copy-neutral loss of heterozygosity and DNA copy number variations in the human genome Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer Somatically acquired structural genetic differences: a longitudinal study of elderly Danish twins Extensive Hidden Genomic Mosaicism Revealed in Normal Tissue The fetal thymus has a unique genomic copy number profile resulting from physiological T cell receptor gene rearrangement Parental somatic mosaicism is underrecognized and influences recurrence risk of genomic disorders Detectable clonal mosaicism in the human genome Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime Abnormal dosage of ultraconserved elements is highly disfavored in healthy cells but not cancer cells Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease Properties and rates of germline mutations in humans Genomic structural variations for cardiovascular and metabolic comorbidity Accumulation of DNA damage in the aged hematopoietic stem cell compartment The ageing genome, clonal mosaicism and chronic disease.The genome-wide landscape of copy number variations in the MUSGEN study provides evidence for a founder effect in the isolated Finnish population.New data shed light on Y-loss-related pathogenesis in myelodysplastic syndromes.How old are you? Genet age estimates in a clonal animal.Detection of Copy Number Alterations Using Single Cell Sequencing Somatic mutations, genome mosaicism, cancer and aging.Natural compounds and aging: between autophagy and inflammasome.Somatic point mutations occurring early in development: a monozygotic twin study.Aging genomes: a necessary evil in the logic of life.Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.

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P2860

Age-related somatic structural changes in the nuclear genome of human blood cells.

http://www.wikidata.org/entity/Q35748382

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Age-related somatic structural changes in the nuclear genome of human blood cells.

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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J.AJHG.2011.12.009

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American Journal of Human Genetics

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Age-related somatic structural changes in the nuclear genome of human blood cells.

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Anna Ronowicz

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Arkadiusz Piotrowski

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Carlos Iribarren

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Chiara Rasi

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Eric Strachan

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Fredrik Eriksson

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Geeta Pakalapati

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Hamid R Razzaghian

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Hemant K Tiwari

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Krista Stanton Thilbeault

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P2860

Epigenetic differences arise during the lifetime of monozygotic twins

Evolution of the mutation rate

Array-based karyotyping for prognostic assessment in chronic lymphocytic leukemia: performance comparison of Affymetrix 10K2.0, 250K Nsp, and SNP6.0 arrays

Cytogenetic features in myelodysplastic syndromes

A new non-linear normalization method for reducing variability in DNA microarray experiments.

Mechanisms and consequences of somatic mosaicism in humans

The influence of age on T cell generation and TCR diversity

Origins and functional impact of copy number variation in the human genome

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Telomeres shorten during ageing of human fibroblasts

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10.1016/J.AJHG.2011.12.009

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2

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90

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Frederick W. Miller

Vilmantas Giedraitis

Lars A Forsberg

Jennifer R Harris

Martin Ingelsson

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2012-02-02T00:00:00Z

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221806124

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