Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection.
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Chagas' disease and AIDSModulation of immune response in experimental Chagas diseaseThe Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruziIL-12p40 deficiency leads to uncontrolled Trypanosoma cruzi dissemination in the spinal cord resulting in neuronal death and motor dysfunctionCD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathyImmunization with cDNA expressed by amastigotes of Trypanosoma cruzi elicits protective immune response against experimental infectionGenes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity.Modulation of CD4(+) T cell-dependent specific cytotoxic CD8(+) T cells differentiation and proliferation by the timing of increase in the pathogen load.A synthetic peptide from Trypanosoma cruzi mucin-like associated surface protein as candidate for a vaccine against Chagas diseaseInduction of IL-12 production in human peripheral monocytes by Trypanosoma cruzi Is mediated by glycosylphosphatidylinositol-anchored mucin-like glycoproteins and potentiated by IFN- γ and CD40-CD40L interactions.Tumor necrosis factor is a therapeutic target for immunological unbalance and cardiac abnormalities in chronic experimental Chagas' heart disease.Inflammasomes in host response to protozoan parasites.Myocardial gene expression of T-bet, GATA-3, Ror-γt, FoxP3, and hallmark cytokines in chronic Chagas disease cardiomyopathy: an essentially unopposed TH1-type response.Chagas disease cardiomyopathy: immunopathology and genetics.NADPH phagocyte oxidase knockout mice control Trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection.Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.Parasite-derived neurotrophic factor/trans-sialidase of Trypanosoma cruzi links neurotrophic signaling to cardiac innate immune responseMacrophage migration inhibitory factor contributes to host defense against acute Trypanosoma cruzi infection.Vaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infectionInducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice.Type I interferons increase host susceptibility to Trypanosoma cruzi infection.NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production.Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunityInterferon-gamma promotes infection of astrocytes by Trypanosoma cruziRequirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.Trypanosoma cruzi evades the protective role of interferon-gamma-signaling in parasite-infected cells.MIF synergizes with Trypanosoma cruzi antigens to promote efficient dendritic cell maturation and IL-12 production via p38 MAPK.Trypanosoma cruzi as an effective cancer antigen delivery vector.IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.Impact of benznidazole on infection course in mice experimentally infected with Trypanosoma cruzi I, II, and IVThe Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazoleRole of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection.Innate and acquired immunity in the pathogenesis of Chagas disease.Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor beta1 deficiency: medical and immunological implications.Probing Trypanosoma cruzi biology with DNA microarrays.Evolution and pathology in chagas disease--a review.Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium.Role of TLRs/MyD88 in host resistance and pathogenesis during protozoan infection: lessons from malaria.Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease.
P2860
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P2860
Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@ast
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@en
type
label
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@ast
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@en
prefLabel
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@ast
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@en
P2093
P2860
P1476
Pivotal role of interleukin-12 ...... g Trypanosoma cruzi infection.
@en
P2093
J Lannes-Vieira
L Q Vieira
R T Gazzinelli
V Michailowsky
P2860
P304
P356
10.1016/S0002-9440(10)63019-2
P407
P577
2001-11-01T00:00:00Z