Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.
about
Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function.Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function.Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38.Design and engineering of deimmunized biotherapeutics.Computationally-driven identification of antibody epitopes.GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing.
P2860
Q35638576-9F28B2B5-4B2F-44A5-B910-9BE818648C87Q36212517-E4AA4476-02FB-422F-9E5F-E58AD122C592Q36945870-3DFC2B2E-2EE3-453F-A11F-682A0A8851FAQ38721404-19A5F2CA-B0FC-4817-A034-DF41BA2BDAFEQ38870681-DACE15EB-1893-42D4-B1A4-7CAFE88BA843Q47098066-61056044-7707-45B0-A134-F9ACFD430461Q47317031-94759185-42A2-4A08-9EBC-D4FB92689E07Q54212204-E52D04C6-BFC9-401A-A184-BC31A609354F
P2860
Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Structure-based redesign of ly ...... vade immune cell surveillance.
@ast
Structure-based redesign of ly ...... vade immune cell surveillance.
@en
type
label
Structure-based redesign of ly ...... vade immune cell surveillance.
@ast
Structure-based redesign of ly ...... vade immune cell surveillance.
@en
prefLabel
Structure-based redesign of ly ...... vade immune cell surveillance.
@ast
Structure-based redesign of ly ...... vade immune cell surveillance.
@en
P2093
P2860
P356
P1476
Structure-based redesign of ly ...... evade immune cell surveillance
@en
P2093
Brent L Berwin
Chris Bailey-Kellogg
Daniel C Osipovitch
Hongliang Zhao
Jennifer Fields
Karl E Griswold
Kristina Blazanovic
Regina S Salvat
Steven N Fiering
P2860
P356
10.1038/MTM.2015.21
P577
2015-06-17T00:00:00Z