Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation
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Association of extracellular matrix proteins fibulin-1 and fibulin-2 with fibronectin in bone marrow stromaVLA-4-mediated interactions between normal human hematopoietic progenitors and stromal cellsTrauma inhibits erythroid burst-forming unit and granulocyte-monocyte colony-forming unit growth through the production of TGF-beta1 by bone marrow stromaMembrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse.Angiogenesis in differentiated placental multipotent mesenchymal stromal cells is dependent on integrin alpha5beta1.VLA-4-dependent myeloma cell adhesion.SAMSN1 is a tumor suppressor gene in multiple myeloma.Survival of B lineage leukemic cells: signals from the bone marrow microenvironment.Regulation of hematopoietic stem cell behavior by the nanostructured presentation of extracellular matrix components.Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.Mechanisms underlying abnormal trafficking and expansion of malignant progenitors in CML: BCR/ABL-induced defects in integrin function in CML.The biology of chronic myelogenous leukemia:mouse models and cell adhesion.Clinical application of hematopoietic progenitor cell expansion: current status and future prospects.Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow.The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironmentAvoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primatesSignaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence.Altered expression of fibronectin and collagens I and IV in multiple myeloma and monoclonal gammopathy of undetermined significance.Adhesion to fibronectin stimulates proliferation of wild-type and bcr/abl-transfected murine hematopoietic cells.Capture and printing of fixed stromal cell membranes for bioactive display on PDMS surfacesAbnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activityBcr/Abl expression stimulates integrin function in hematopoietic cell linesExtracellular matrix protein Reelin promotes myeloma progression by facilitating tumor cell proliferation and glycolysis.Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of β1-Integrin Activation.The plasminogen system in regulating stem cell mobilization.Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy.Effects of Mesenchymal Stem Cell Derivatives on Hematopoiesis and Hematopoietic Stem Cells.Apoptotic death of hematopoietic tumor cells through potentiated and sustained adhesion to fibronectin via VLA-4Soluble factor(s) produced by adult bone marrow stroma inhibit in vitro proliferation and differentiation of fetal liver BFU-E by inducing apoptosis.Dose-dependent effects of Bcr-Abl in cell line models of different stages of chronic myeloid leukemia.The microenvironment of AFT024 cells maintains primitive human hematopoiesis by counteracting contact mediated inhibition of proliferation.Differential use of very late antigen-4 and -5 integrins by hematopoietic precursors and myeloma cells to adhere to transforming growth factor-beta1-treated bone marrow stroma.Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines.TGF-beta1-binding proteins on human bone marrow stromal cells.The effect of interferon-alpha on beta-1 integrin mediated adhesion and growth regulation in chronic myelogenous leukemia.A novel region of the alpha4 integrin subunit with a modulatory role in VLA-4-mediated cell adhesion to fibronectin.Abnormal growth factor modulation of beta1-integrin-mediated adhesion in chronic myelogenous leukaemia haematopoietic progenitors.
P2860
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P2860
Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@ast
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@en
type
label
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@ast
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@en
prefLabel
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@ast
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@en
P2093
P2860
P356
P1476
Direct adhesion to bone marrow ...... ietic progenitor proliferation
@en
P2093
C M Verfaillie
J B McCarthy
R W Hurley
P2860
P304
P356
10.1172/JCI118063
P407
P577
1995-07-01T00:00:00Z