Differences in prion strain conformations result from non-native interactions in a nucleus.
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Identification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-IUbiquitous amyloidsStepwise organization of the β-structure identifies key regions essential for the propagation and cytotoxicity of insulin amyloid fibrils.[PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domain.Analysis of the [RNQ+] prion reveals stability of amyloid fibers as the key determinant of yeast prion variant propagation.Mysterious oligomerization of the amyloidogenic proteinsPrionHome: a database of prions and other sequences relevant to prion phenomena.Amyloid structure: conformational diversity and consequences.Orientation of aromatic residues in amyloid cores: structural insights into prion fiber diversityDistinct amino acid compositional requirements for formation and maintenance of the [PSI⁺] prion in yeast.Increasing prion propensity by hydrophobic insertion.Structural complexity of a composite amyloid fibril.Amino acid composition predicts prion activityHuman J-protein DnaJB6b Cures a Subset of Saccharomyces cerevisiae Prions and Selectively Blocks Assembly of Structurally Related Amyloids.A Decentralized Approach to the Formulation of Hypotheses: A Hierarchical Structural Model for a Prion Self-Assembled SystemIon-specific effects on prion nucleation and strain formation.Soluble oligomers are sufficient for transmission of a yeast prion but do not confer phenotype.Structural and functional characterization of two alpha-synuclein strains.Variant-specific prion interactions: Complicating factors.Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's diseaseEmergence and natural selection of drug-resistant prions.Nanoimaging for prion related diseases.A bipolar personality of yeast prion proteins.Prion formation by a yeast GLFG nucleoporin.Expanding the yeast prion world: Active prion conversion of non-glutamine/asparagine-rich Mod5 for cell survival.Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions.Site-specific structural analysis of a yeast prion strain with species-specific seeding activity.Strain conformation controls the specificity of cross-species prion transmission in the yeast modelChaperone proteins select and maintain [PIN+] prion conformations in Saccharomyces cerevisiae.The effects of amino acid composition on yeast prion formation and prion domain interactionsStructural definition is important for the propagation of the yeast [PSI+] prion.The conformation of the prion domain of Sup35p in isolation and in the full-length protein.Active conversion to the prion state as a molecular switch for cellular adaptation to environmental stress.Initial condition of stochastic self-assembly.Layers of structure and function in protein aggregation.Molecular basis for diversification of yeast prion strain conformation.Prion replication in the mammalian cytosol: Functional regions within a prion domain driving induction, propagation and inheritance.
P2860
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P2860
Differences in prion strain conformations result from non-native interactions in a nucleus.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Differences in prion strain co ...... ive interactions in a nucleus.
@ast
Differences in prion strain co ...... ive interactions in a nucleus.
@en
type
label
Differences in prion strain co ...... ive interactions in a nucleus.
@ast
Differences in prion strain co ...... ive interactions in a nucleus.
@en
prefLabel
Differences in prion strain co ...... ive interactions in a nucleus.
@ast
Differences in prion strain co ...... ive interactions in a nucleus.
@en
P2093
P2860
P356
P1476
Differences in prion strain co ...... ive interactions in a nucleus.
@en
P2093
Brandon H Toyama
Kazuki Ito
Motomasa Tanaka
Yumiko Ohhashi
P2860
P2888
P304
P356
10.1038/NCHEMBIO.306
P577
2010-01-17T00:00:00Z