Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.
about
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and functionIdentifying key residues of sphinganine-1-phosphate lyase for function in vivo and in vitro.Metabolomics to unveil and understand phenotypic diversity between pathogen populationsDe novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes.SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.Developmentally regulated sphingolipid degradation in Leishmania majorDegradation of host sphingomyelin is essential for Leishmania virulence.Phospholipid and sphingolipid metabolism in Leishmania.Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei.Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invasionSphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liverMolecular evolution of the enzymes involved in the sphingolipid metabolism of Leishmania: selection pressure in relation to functional divergence and conservation.Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.Metabolic variation during development in culture of Leishmania donovani promastigotes.Sphingolipids in parasitic protozoaATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania majorLeishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment.An update on sphingosine-1-phosphate and other sphingolipid mediators.Transbilayer dynamics of phospholipids in the plasma membrane of the Leishmania genusMetabolic reprogramming during purine stress in the protozoan pathogen Leishmania donovaniSphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.Amino acid determinants of substrate selectivity in the Trypanosoma brucei sphingolipid synthase family.Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania majorTruth and consequences of sphingosine-1-phosphate lyase.Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi.Developmentally regulated sphingolipid synthesis in African trypanosomesPlasmenylethanolamine synthesis in Leishmania major.Lipidomic analysis of bloodstream and procyclic form Trypanosoma bruceiLipid metabolism in Trypanosoma bruceiLeishmania sand fly interaction: progress and challenges.Sphingosine-1-phosphate lyase in development and disease: sphingolipid metabolism takes flight.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansSphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expressionLyase to live by: sphingosine phosphate lyase as a therapeutic target.Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrateSphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence.Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondiiLeishmania amazonensis exhibits phosphatidylserine-dependent procoagulant activity, a process that is counteracted by sandfly saliva.Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis.Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition.
P2860
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P2860
Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@ast
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@en
type
label
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@ast
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@en
prefLabel
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@ast
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@en
P2093
P2860
P921
P356
P1433
P1476
Redirection of sphingolipid me ...... of ethanolamine in Leishmania.
@en
P2093
Fong-Fu Hsu
Julie D Saba
Justine M Pompey
Padmavathi Bandhuvula
Phillip Key
P2860
P304
P356
10.1038/SJ.EMBOJ.7601565
P407
P577
2007-02-08T00:00:00Z