Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development. - Wikidata - awgldk - TriplyDB

Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development.

Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development.

http://www.wikidata.org/entity/Q35753309

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AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression Overexpression of matrix metalloproteinase-10 and matrix metalloproteinase-3 in human diabetic corneas: a possible mechanism of basement membrane and integrin alterations Putting tumours in context A functional overlap of plasminogen and MMPs regulates vascularization during placental development Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging.An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer immunological prevention An odyssey from breast to bone: multi-step control of mammary metastases and osteolysis by matrix metalloproteinases.Plasticity of mammary epithelia during normal development and neoplastic progression.Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells.Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment The structural and mechanical complexity of cell-growth control.The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis.Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis.The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter.Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones Proteinases, cell cycle regulation, and apoptosis during mammary gland involution (minireview).Cancer associated fibroblasts (CAFs) in tumor microenvironment.The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis Transcriptional regulation of stromelysin-1 gene expression is altered during progression of mouse mammary epithelial cells from functionally normal to malignant.Tissue architecture: the ultimate regulator of breast epithelial function.Communication between the cell membrane and the nucleus: role of protein compartmentalization.Order and disorder: the role of extracellular matrix in epithelial cancer.Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation Nidogen-1 regulates laminin-1-dependent mammary-specific gene expression.Matrix metalloproteinase-induced genomic instability Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution Matrix metalloproteinases in tumorigenesis: an evolving paradigm.The dominance of the microenvironment in breast and ovarian cancer.Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis.Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil.Tenascin-C: Exploitation and collateral damage in cancer management Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution.Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6 Tumour-stromal interactions in breast cancer: the role of stroma in tumourigenesis.Stromelysin-1 regulates adipogenesis during mammary gland involution Host epithelial geometry regulates breast cancer cell invasiveness.184AA3: a xenograft model of ER+ breast adenocarcinoma.

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P2860

Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development.

http://www.wikidata.org/entity/Q35753309

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene.

The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture.

Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.

Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.

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