The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain
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A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood in animal models of depressionEnhanced AMPA receptor-mediated neurotransmission on CA1 pyramidal neurons during status epilepticus.NMDA receptor regulation of cell death in the rat olfactory bulb.The effect of MK-801 on kindled seizures: implications for use and limitations as an antiepileptic drug.Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.In vitro and in vivo characterization of [3H]CNS-5161--a use-dependent ligand for the N-methyl-D-aspartate receptor in rat brain.Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.Interaction of [3H]MK-801 with multiple states of the N-methyl-D-aspartate receptor complex of rat brainSelective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging.Interaction of the NMDA receptor noncompetitive antagonist MK-801 with model and native membranes.Remacemide: current status and clinical applications.Spermine modulation of the glutamate(NMDA) receptor is differentially responsive to conantokins in normal and Alzheimer's disease human cerebral cortex.Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects.3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycineKetamine and phencyclidine: the good, the bad and the unexpected.Neuropathology in Drosophila membrane excitability mutantsNicotine exposure refines visual map topography through an NMDA receptor-mediated pathway.Further insights into the anti-aggregating activity of NMDA in human platelets.Modulation by magnesium of N-methyl-D-aspartate receptors in developing human brain.Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor.Neuroendocrine mechanism of onset of puberty. Sequential reduction in activity of inhibitory and facilitatory N-methyl-D-aspartate receptorsQuantitative autoradiography of [3H]-MK-801 binding sites in mammalian brainTricyclic antidepressants block N-methyl-D-aspartate receptors: similarities to the action of zinc.Postnatal changes in N-methyl-D-aspartate receptor binding and stimulation by glutamate and glycine of [3H]-MK-801 binding in human temporal cortexInhibition of cortical spreading depression by L-701,324, a novel antagonist at the glycine site of the N-methyl-D-aspartate receptor complex.Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.Mechanisms of synaptic plasticity. Changes in postsynaptic densities and glutamate receptors in chicken forebrain during maturation.Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain.Dynamic changes in N-methyl-D-aspartate receptors after closed head injury in mice: Implications for treatment of neurological and cognitive deficits.Challenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective.Excitatory amino acid receptor subtypes and specific antagonists.Identification of genes regulated by memantine and MK-801 in adult rat brain by cDNA microarray analysis.Amphetamine and dopamine-induced immediate early gene expression in striatal neurons depends on postsynaptic NMDA receptors and calcium.Ca2+ entry pathways in mouse spinal motor neurons in culture following in vitro exposure to methylmercury.N-methyl-D-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation.Regional variations in [3H]MK801 binding to rat brain N-methyl-D-aspartate receptors.Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes.6,7-Dichloroquinoxaline-2,3-dione is a competitive antagonist specific to strychnine-insensitive [3H]glycine binding sites on the N-methyl-D-aspartate receptor complex.Effects of pH on the actions of dizocilpine at the N-methyl-D-aspartate receptor complex.
P2860
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P2860
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@ast
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@en
type
label
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@ast
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@en
prefLabel
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@ast
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@en
P2860
P1476
The novel anticonvulsant MK-80 ...... spartate receptor in rat brain
@en
P2093
P2860
P304
P356
10.1111/J.1476-5381.1987.TB10295.X
P407
P577
1987-06-01T00:00:00Z