Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate. - Wikidata - awgldk - TriplyDB

Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate.

Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate.

http://www.wikidata.org/entity/Q35754758

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Role of K ATP channels in cephalic vasodilatation induced by calcitonin gene-related peptide, nitric oxide, and transcranial electrical stimulation in the rat.Potassium channel activators and bronchial asthma.Potassium channel openers: pharmacological and clinical aspects.The negative inotropic effect of nicorandil is independent of cyclic GMP changes: a comparison with pinacidil and cromakalim in canine atrial muscle.Interaction of potassium channel openers and blockers in canine atrial muscle.Effects of putative activators of K+ channels in mouse pancreatic beta-cells.Endothelium-dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization.Effects of cromakalim on neurally-mediated responses of guinea-pig tracheal smooth muscle Potassium channel activator drugs: mechanism of action, pharmacological properties, and therapeutic potential.Evidence that pinacidil may promote the opening of ATP-sensitive K+ channels yet inhibit the opening of Ca2(+)-activated K+ channels in K(+)-contracted canine mesenteric artery Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil.Haemodynamic profile of the potassium channel activator EMD 52692 in anaesthetized pigs.Pinacidil inhibits neuromuscular transmission indirectly in the guinea-pig and rabbit mesenteric arteries.Effects of the novel potassium channel opener, UR-8225, on contractile responses in rat isolated smooth muscle Pharmacology of the potassium channel openers.Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.Age-dependence of the effects of pinacidil on rat aorta.Pinacidil opens K+-selective channels causing hyperpolarization and relaxation of noradrenaline contractions in rat mesenteric resistance vessels.Effects of BRL 38227 on neurally-mediated responses in the guinea-pig isolated bronchus.Effect of K+ channel-modulating drugs on the vasoconstrictor responses of leukotrienes C4, D4 and angiotensin II in the guinea-pig isolated perfused heart.Effect of cromakalim on contractions in rabbit isolated renal artery in the presence and absence of extracellular Ca2+.Cardiovascular effects of apamin and BRL 34915 in rats and rabbits.Influence of osmolarity of solutions used for K+ contraction on relaxant responses to pinacidil, verapamil, theophylline and terbutaline in isolated airway smooth muscle.Inhibition by sulphonylureas of vasorelaxation induced by K+ channel activators in vitro.Antispasmodic effects of the essential oil of Croton nepetaefolius on guinea-pig ileum: a myogenic activity.Pinacidil uptake and effects in the isolated rabbit heart.Effects of potassium channel openers and calcium channel blockers on the force responses of the electrically driven rat right ventricle strip.The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs.Differential relaxant responses to pinacidil of smooth muscle preparations contracted by a high concentration of potassium in isoosmolar and hyperosmolar solutions.Acute hemodynamic effects of pinacidil in hypertensive patients with and without propranolol pretreatment.

P2860

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P2860

Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate.

http://www.wikidata.org/entity/Q35754758

description

1987 nî lūn-bûn

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1987年の論文

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1987年論文

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1987年論文

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1987年論文

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1987年論文

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1987年論文

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1987年论文

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1987年论文

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1987年论文

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J.1476-5381.1987.TB10297.X

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British Journal of Pharmacology

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P2860

Cyclic guanosine monophosphate as a mediator of vasodilation

Mechanical and electrical aspects of the relaxant action of aminophylline in guinea-pig isolated trachealis.

Electrical and mechanical effects of BRL34915 in guinea-pig isolated trachealis.

Effect of apamin on responses to BRL 34915, nicorandil and other relaxants in the guinea-pig taenia caeci.

Evidence that the spasmogenic action of tetraethylammonium in guinea-pig trachealis is both direct and dependent on the cellular influx of calcium ion.

Lack of correlation between cyclic GMP elevation and relaxation of nonvascular smooth muscle by nitroglycerin, nitroprusside, hydroxylamine and sodium azide.

Some effects of sodium nitroprusside, methoxyverapamil (D600) and nifedipine on rat portal vein.

Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein.

The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels

Systemic and coronary hemodynamic effects of pinacidil, a new antihypertensive agent, in awake dogs: comparison with hydralazine.

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