Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling.
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Membrane estrogen receptor-alpha levels in MCF-7 breast cancer cells predict cAMP and proliferation responses.Epidermal growth factor directs sex-specific steroid signaling through Src activationH3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependencySplice isoform estrogen receptors as integral transmembrane proteinsG protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhageMembrane estrogen receptor-alpha levels predict estrogen-induced ERK1/2 activation in MCF-7 cellsReduction of post injury neointima formation due to 17beta-estradiol and phytoestrogen treatment is not influenced by the pure synthetic estrogen receptor antagonist ICI 182,780 in vitroImportance of Estrogenic Signaling and Its Mediated Receptors in Prostate CancerInsulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects.Differential ligand binding affinities of human estrogen receptor-α isoformsPulmonary Arterial Hypertension and the Sex Hormone Paradox.Estrogen facilitates spinal cord synaptic transmission via membrane-bound estrogen receptors: implications for pain hypersensitivity.Epitope-dependent localization of estrogen receptor-alpha, but not -beta, in en face arterial endothelium.Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1.Estrogen attenuates chronic volume overload induced structural and functional remodeling in male rat hearts.Endothelial estrogen receptor isoforms and cardiovascular diseaseEstrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells of the rat uterus.PDE5 inhibitor efficacy is estrogen dependent in female heart disease.Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuseEstrogen actions on neuroendocrine glia.Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways.The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in miceProteins of multiple classes may participate in nongenomic steroid actions.Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes.17Beta-estradiol elevates cGMP and, via plasma membrane recruitment of protein kinase GIalpha, stimulates Ca2+ efflux from rat hepatocytes.Estrogen receptor mutations and changes in downstream gene expression and signalingDirect effects of estrogen on the vessel wall.Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells.Postmenopausal oestrogen replacement therapy and atherosclerosis: can current compounds provide cardiovascular protection?Cell surface estrogen receptor alpha is upregulated during subchronic metabolic stress and inhibits neuronal cell degenerationCell localization, physiology, and nongenomic actions of estrogen receptors.Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesisSoluble guanylate cyclase as a novel treatment target for osteoporosis.Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells.Nitric oxide signalling is involved in diarylheptanoid-induced increases in femoral arterial blood flow in ovariectomized rats.Estradiol rapidly inhibits soluble guanylyl cyclase expression in rat uterus.A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling.Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts.Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells.
P2860
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P2860
Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Human vascular endothelial cel ...... rapid intracellular signaling.
@ast
Human vascular endothelial cel ...... rapid intracellular signaling.
@en
type
label
Human vascular endothelial cel ...... rapid intracellular signaling.
@ast
Human vascular endothelial cel ...... rapid intracellular signaling.
@en
prefLabel
Human vascular endothelial cel ...... rapid intracellular signaling.
@ast
Human vascular endothelial cel ...... rapid intracellular signaling.
@en
P2093
P2860
P356
P1476
Human vascular endothelial cel ...... rapid intracellular signaling.
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.11.5930
P407
P577
2000-05-01T00:00:00Z