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Tissue Regeneration in the Chronically Inflamed Tumor Environment: Implications for Cell Fusion Driven Tumor Progression and Therapy Resistant Tumor Hybrid CellsShift and adapt: the costs and benefits of karyotype variationsYeast: a simple model system to study complex phenomena of aneuploidyThe ancient and evolving roles of cohesin in gene expression and DNA repairEvolution of the cancer genomeCoping with stress and the emergence of multidrug resistance in fungiRe-replication of a centromere induces chromosomal instability and aneuploidyA tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazoleChromothripsis from DNA damage in micronuclei.Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformansImportance of Polη for damage-induced cohesion reveals differential regulation of cohesion establishment at the break site and genome-wideGenetic instability in budding and fission yeast-sources and mechanismsMutational landscape of yeast mutator strainsCurrent understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessmentUnique features of the transcriptional response to model aneuploidy in human cellsNeocentromeres Provide Chromosome Segregation Accuracy and Centromere Clustering to Multiple Loci along a Candida albicans ChromosomeAneuploidy Causes Non-genetic IndividualityLoss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathwaySegmental Duplication of Chromosome 11 and its Implications for Cell Division and Genome-wide Expression in Rice.A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male miceA shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brainQuantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing proteinA lysine deacetylase Hos3 is targeted to the bud neck and involved in the spindle position checkpointSynthetic lethality of cohesins with PARPs and replication fork mediators.Sgs1 and Exo1 suppress targeted chromosome duplication during ends-in and ends-out gene targeting.Karyotypic determinants of chromosome instability in aneuploid budding yeast.Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients.The CCR4-NOT complex is implicated in the viability of aneuploid yeasts.Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosityThiol peroxidase deficiency leads to increased mutational load and decreased fitness in Saccharomyces cerevisiae.Elite model for the generation of induced pluripotent cancer cells (iPCs).Copy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae.Transcriptional consequence and impaired gametogenesis with high-grade aneuploidy in Arabidopsis thalianaChromosome-wide aneuploidy study of cultured circulating myeloid progenitor cells from workers occupationally exposed to formaldehyde.Chromosomal copy number variation, selection and uneven rates of recombination reveal cryptic genome diversity linked to pathogenicity.Initiation of DNA replication from non-canonical sites on an origin-depleted chromosomeUbiquitin ligase Ufd2 is required for efficient degradation of Mps1 kinase.
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description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Aneuploidy drives genomic instability in yeast.
@ast
Aneuploidy drives genomic instability in yeast.
@en
type
label
Aneuploidy drives genomic instability in yeast.
@ast
Aneuploidy drives genomic instability in yeast.
@en
prefLabel
Aneuploidy drives genomic instability in yeast.
@ast
Aneuploidy drives genomic instability in yeast.
@en
P2093
P2860
P50
P356
P1433
P1476
Aneuploidy drives genomic instability in yeast.
@en
P2093
Benson M George
Heidi M Blank
Jason M Sheltzer
Osami Niwa
Sarah J Pfau
Yoshie Tange
P2860
P304
P356
10.1126/SCIENCE.1206412
P407
P577
2011-08-01T00:00:00Z