Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. - Wikidata - awgldk - TriplyDB

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.

http://www.wikidata.org/entity/Q35757097

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Modulation of glucose metabolism by the renin-angiotensin-aldosterone system Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs DC260126: a small-molecule antagonist of GPR40 that protects against pancreatic β-Cells dysfunction in db/db mice Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction Angiotensin-(1-7) suppresses the number and function of the circulating fibrocytes by upregulating endothelial nitric oxide synthase expression.Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders Classical Renin-Angiotensin system in kidney physiology ACE2 and diabetes: ACE of ACEs?Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism.Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice.Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets.Renin-angiotensin system blockers protect pancreatic islets against diet-induced obesity and insulin resistance in mice A systematic review of the role of renin angiotensin aldosterone system genes in diabetes mellitus, diabetic retinopathy and diabetic neuropathy Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays Loss of prolyl carboxypeptidase in two-kidney, one-clip goldblatt hypertensive mice The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos.Overproduction of angiotensinogen from adipose tissue induces adipose inflammation, glucose intolerance, and insulin resistance.The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome Angiotensin converting enzyme 2: a new important player in the regulation of glycemia.ACE2 deficiency reduces β-cell mass and impairs β-cell proliferation in obese C57BL/6 mice Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice.Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice.The renin angiotensin aldosterone system and insulin resistance in humans.Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice.Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet.Antioxidant effect of angiotensin (1‑7) in the protection of pancreatic β cell function.New agents modulating the renin-angiotensin-aldosterone system-Will there be a new therapeutic option?Recombinant Reg3β protein protects against streptozotocin-induced β-cell damage and diabetes.Characterization of ACE and ACE2 Expression within Different Organs of the NOD Mouse Apelin, diabetes, and obesity.The renin-angiotensin system: a link between obesity, inflammation and insulin resistance.Brain renin-angiotensin system in the nexus of hypertension and aging Angiotensin-(1-7): beyond the cardio-renal actions.Modulation of the action of insulin by angiotensin-(1-7).Angiotensin-converting enzyme 2 and angiotensin 1-7: novel therapeutic targets.Targeting angiotensin-converting enzyme 2 as a new therapeutic target for cardiovascular diseases.

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P2860

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.

http://www.wikidata.org/entity/Q35757097

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Angiotensin I-converting enzym ...... emic control in diabetic mice.

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Angiotensin I-converting enzym ...... emic control in diabetic mice.

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Angiotensin I-converting enzym ...... emic control in diabetic mice.

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Angiotensin I-converting enzym ...... emic control in diabetic mice.

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A Hamid Boulares

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Chetan P Hans

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Eric Lazartigues

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Huijing Xia

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Sharell M Bindom

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P2860

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys

Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor

Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells.

Selective gene transfer to key cardiovascular regions of the brain: comparison of two viral vector systems.

Viral vectors for gene delivery and gene therapy within the endocrine system.

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